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Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting

Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting

In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell sorting, while also increasing the spatial resolution for multiscale sorting.

1932-1058
Holloway, Paul M.
59a865d9-08bc-43c7-aa00-d80509956d86
Butement, Jonathan
581ce321-f1af-4a2f-870a-9d8d45133586
Hegde, Manjunath
8d164e37-3839-4f27-b13d-1c0de5ee8ae2
West, Jonathan
f1c2e060-16c3-44c0-af70-242a1c58b968
Holloway, Paul M.
59a865d9-08bc-43c7-aa00-d80509956d86
Butement, Jonathan
581ce321-f1af-4a2f-870a-9d8d45133586
Hegde, Manjunath
8d164e37-3839-4f27-b13d-1c0de5ee8ae2
West, Jonathan
f1c2e060-16c3-44c0-af70-242a1c58b968

Holloway, Paul M., Butement, Jonathan, Hegde, Manjunath and West, Jonathan (2018) Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting. Biomicrofluidics, 12 (4), [044104]. (doi:10.1063/1.5038965).

Record type: Article

Abstract

In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell sorting, while also increasing the spatial resolution for multiscale sorting.

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Accepted/In Press date: 24 June 2018
e-pub ahead of print date: 9 July 2018
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Identifiers

Local EPrints ID: 422695
URI: http://eprints.soton.ac.uk/id/eprint/422695
DOI: doi:10.1063/1.5038965
ISSN: 1932-1058
PURE UUID: b8c649de-d43a-4a30-a243-27d3b29bc972
ORCID for Jonathan West: ORCID iD orcid.org/0000-0002-5709-6790

Catalogue record

Date deposited: 31 Jul 2018 16:30
Last modified: 16 Mar 2024 04:12

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Contributors

Author: Paul M. Holloway
Author: Jonathan Butement
Author: Manjunath Hegde
Author: Jonathan West ORCID iD

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