The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium
The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium
The multinational SYSCILIA consortium aims to gain a mechanistic understanding of the cilium. We utilize multiple parallel high-throughput (HTP) initiatives to develop predictive models of relationships between complex genotypes and variable phenotypes of ciliopathies. The models generated are only as good as the wet laboratory data fed into them. It is therefore essential to orchestrate a well-annotated and high-confidence dataset to be able to assess the quality of any HTP dataset. Here, we present the inaugural SYSCILIA gold standard of known ciliary components as a public resource.
van Dam, Teunis J.P.
19685c54-2a38-4717-a85a-1b85d6bc0d18
Wheway, Gabrielle
2e547e5d-b921-4243-a071-2208fd4cc090
Slaats, Gisela G.
9d68108a-71e6-4108-b045-f4618d86ceae
Huynen, Martijn A.
68265332-86ae-4446-b17c-99844a27a3cb
Giles, Rachel H.
bd549bac-2cb3-4209-8373-e12ba63c2f17
31 May 2013
van Dam, Teunis J.P.
19685c54-2a38-4717-a85a-1b85d6bc0d18
Wheway, Gabrielle
2e547e5d-b921-4243-a071-2208fd4cc090
Slaats, Gisela G.
9d68108a-71e6-4108-b045-f4618d86ceae
Huynen, Martijn A.
68265332-86ae-4446-b17c-99844a27a3cb
Giles, Rachel H.
bd549bac-2cb3-4209-8373-e12ba63c2f17
van Dam, Teunis J.P., Wheway, Gabrielle, Slaats, Gisela G., Huynen, Martijn A. and Giles, Rachel H.
,
SYSCILIA Study Group
(2013)
The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium.
Cilia, 2 (1).
(doi:10.1186/2046-2530-2-7).
Abstract
The multinational SYSCILIA consortium aims to gain a mechanistic understanding of the cilium. We utilize multiple parallel high-throughput (HTP) initiatives to develop predictive models of relationships between complex genotypes and variable phenotypes of ciliopathies. The models generated are only as good as the wet laboratory data fed into them. It is therefore essential to orchestrate a well-annotated and high-confidence dataset to be able to assess the quality of any HTP dataset. Here, we present the inaugural SYSCILIA gold standard of known ciliary components as a public resource.
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Accepted/In Press date: 28 May 2013
e-pub ahead of print date: 31 May 2013
Published date: 31 May 2013
Identifiers
Local EPrints ID: 423518
URI: http://eprints.soton.ac.uk/id/eprint/423518
ISSN: 2046-2530
PURE UUID: 6fda1fb5-67e8-4823-8898-0a644f2b9409
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Date deposited: 25 Sep 2018 16:30
Last modified: 16 Mar 2024 04:38
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Contributors
Author:
Teunis J.P. van Dam
Author:
Gisela G. Slaats
Author:
Martijn A. Huynen
Author:
Rachel H. Giles
Corporate Author: SYSCILIA Study Group
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