Amino acids in Tanzanian children with sickle cell disease: baseline results of the Vascular Function Intervention Trial (V-FIT)
Amino acids in Tanzanian children with sickle cell disease: baseline results of the Vascular Function Intervention Trial (V-FIT)
Poor nutritional status is common in SCD but there are no strategies to improve nutrition. Vascular function is also impaired and may underlie SCD related complications. V-FIT (NCT01718054) is a double blind, random order, cross over trial of a daily ready-to-use supplementary food (RUSF) (500 kcal, 1 RDA vits & minerals, 1mg folate, Nutriset) and the same RUSF fortified with arginine & citrulline (RUSFv, 0.2g/kg/d & 0.1g/kg/d), designed to improve growth and vascular function. Here we report baseline amino acid profiles, nutritional status and their association in children enrolled in V-FIT.
Marealle, Alphonce
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Makani, Julie
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Kirkham, Fenella
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Prentice, Andrew
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Cox, Sharon
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April 2015
Marealle, Alphonce
f9c64613-bce6-49f0-a6f1-f70b713b6d75
Makani, Julie
76a145a7-02fc-43ea-a1df-3a52d2004e48
Kirkham, Fenella
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58
Prentice, Andrew
6b851f61-f989-48f6-8109-9a7408254728
Cox, Sharon
7fa93ab4-386b-4c7d-9a19-2138fb7a3fce
Marealle, Alphonce, Makani, Julie, Kirkham, Fenella, Prentice, Andrew and Cox, Sharon
(2015)
Amino acids in Tanzanian children with sickle cell disease: baseline results of the Vascular Function Intervention Trial (V-FIT).
The FASEB Journal, 29 (1 supplement).
Abstract
Poor nutritional status is common in SCD but there are no strategies to improve nutrition. Vascular function is also impaired and may underlie SCD related complications. V-FIT (NCT01718054) is a double blind, random order, cross over trial of a daily ready-to-use supplementary food (RUSF) (500 kcal, 1 RDA vits & minerals, 1mg folate, Nutriset) and the same RUSF fortified with arginine & citrulline (RUSFv, 0.2g/kg/d & 0.1g/kg/d), designed to improve growth and vascular function. Here we report baseline amino acid profiles, nutritional status and their association in children enrolled in V-FIT.
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Published date: April 2015
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Local EPrints ID: 424296
URI: http://eprints.soton.ac.uk/id/eprint/424296
ISSN: 0892-6638
PURE UUID: 18eba142-789a-4a34-ac00-17415d3a4898
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Date deposited: 05 Oct 2018 11:35
Last modified: 16 Mar 2024 03:22
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Contributors
Author:
Alphonce Marealle
Author:
Julie Makani
Author:
Andrew Prentice
Author:
Sharon Cox
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