Session 2: Mutational discordance: the big challenge in personalized treatments – any solutions?
Session 2: Mutational discordance: the big challenge in personalized treatments – any solutions?
The great challenge for oncologists treating patients who are developing or progressing with metastatic disease is to be able to offer a truly personalized and targeted therapy that can have an early and meaningful effect on the course of the disease. At present the known molecular markers are limited in their frequency and reliability in determining the use of newer chemotherapies. Professor Eng discusses the challenges faced in ensuring timely and effective treatments based on the molecular profile of the tumour and the potential role of real-time analysis of mutational changes in the tumour when progression occurs.
49-51
Siddiqui, M.
2256133d-5c71-43c4-a01c-e7502b780bcb
Chand, M.
93e8b2a3-62c0-4f73-b1fe-df18435c4611
Eng, C.
04f78095-448a-4d94-ba1b-a0d4cd26e9d4
Mehdizadeh, A.
48437b9b-1de9-45fc-8683-5069f384e5a9
Mirnezami, A.
b3c7aee7-46a4-404c-bfe3-f72388e0bc94
Brown, G.
d4e78f7b-7064-42db-bc4c-caf08df4bfbe
May 2018
Siddiqui, M.
2256133d-5c71-43c4-a01c-e7502b780bcb
Chand, M.
93e8b2a3-62c0-4f73-b1fe-df18435c4611
Eng, C.
04f78095-448a-4d94-ba1b-a0d4cd26e9d4
Mehdizadeh, A.
48437b9b-1de9-45fc-8683-5069f384e5a9
Mirnezami, A.
b3c7aee7-46a4-404c-bfe3-f72388e0bc94
Brown, G.
d4e78f7b-7064-42db-bc4c-caf08df4bfbe
Siddiqui, M., Chand, M., Eng, C., Mehdizadeh, A., Mirnezami, A. and Brown, G.
(2018)
Session 2: Mutational discordance: the big challenge in personalized treatments – any solutions?
Colorectal Disease, 20 (S1), .
(doi:10.1111/codi.14079).
Abstract
The great challenge for oncologists treating patients who are developing or progressing with metastatic disease is to be able to offer a truly personalized and targeted therapy that can have an early and meaningful effect on the course of the disease. At present the known molecular markers are limited in their frequency and reliability in determining the use of newer chemotherapies. Professor Eng discusses the challenges faced in ensuring timely and effective treatments based on the molecular profile of the tumour and the potential role of real-time analysis of mutational changes in the tumour when progression occurs.
This record has no associated files available for download.
More information
e-pub ahead of print date: 24 May 2018
Published date: May 2018
Identifiers
Local EPrints ID: 424855
URI: http://eprints.soton.ac.uk/id/eprint/424855
ISSN: 1462-8910
PURE UUID: 771b9208-524d-4d2e-bb3e-59332e32fa59
Catalogue record
Date deposited: 05 Oct 2018 11:50
Last modified: 15 Mar 2024 20:21
Export record
Altmetrics
Contributors
Author:
M. Siddiqui
Author:
M. Chand
Author:
C. Eng
Author:
A. Mehdizadeh
Author:
G. Brown
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics