The University of Southampton
University of Southampton Institutional Repository

Session 2: Mutational discordance: the big challenge in personalized treatments – any solutions?

Session 2: Mutational discordance: the big challenge in personalized treatments – any solutions?
Session 2: Mutational discordance: the big challenge in personalized treatments – any solutions?

The great challenge for oncologists treating patients who are developing or progressing with metastatic disease is to be able to offer a truly personalized and targeted therapy that can have an early and meaningful effect on the course of the disease. At present the known molecular markers are limited in their frequency and reliability in determining the use of newer chemotherapies. Professor Eng discusses the challenges faced in ensuring timely and effective treatments based on the molecular profile of the tumour and the potential role of real-time analysis of mutational changes in the tumour when progression occurs.

1462-8910
49-51
Siddiqui, M.
2256133d-5c71-43c4-a01c-e7502b780bcb
Chand, M.
93e8b2a3-62c0-4f73-b1fe-df18435c4611
Eng, C.
04f78095-448a-4d94-ba1b-a0d4cd26e9d4
Mehdizadeh, A.
48437b9b-1de9-45fc-8683-5069f384e5a9
Mirnezami, A.
b3c7aee7-46a4-404c-bfe3-f72388e0bc94
Brown, G.
53955d91-4bfb-4b58-8aec-697cd0ee2593
Siddiqui, M.
2256133d-5c71-43c4-a01c-e7502b780bcb
Chand, M.
93e8b2a3-62c0-4f73-b1fe-df18435c4611
Eng, C.
04f78095-448a-4d94-ba1b-a0d4cd26e9d4
Mehdizadeh, A.
48437b9b-1de9-45fc-8683-5069f384e5a9
Mirnezami, A.
b3c7aee7-46a4-404c-bfe3-f72388e0bc94
Brown, G.
53955d91-4bfb-4b58-8aec-697cd0ee2593

Siddiqui, M., Chand, M., Eng, C., Mehdizadeh, A., Mirnezami, A. and Brown, G. (2018) Session 2: Mutational discordance: the big challenge in personalized treatments – any solutions? Colorectal Disease, 20 (S1), 49-51. (doi:10.1111/codi.14079).

Record type: Article

Abstract

The great challenge for oncologists treating patients who are developing or progressing with metastatic disease is to be able to offer a truly personalized and targeted therapy that can have an early and meaningful effect on the course of the disease. At present the known molecular markers are limited in their frequency and reliability in determining the use of newer chemotherapies. Professor Eng discusses the challenges faced in ensuring timely and effective treatments based on the molecular profile of the tumour and the potential role of real-time analysis of mutational changes in the tumour when progression occurs.

Full text not available from this repository.

More information

e-pub ahead of print date: 24 May 2018
Published date: May 2018

Identifiers

Local EPrints ID: 424855
URI: https://eprints.soton.ac.uk/id/eprint/424855
ISSN: 1462-8910
PURE UUID: 771b9208-524d-4d2e-bb3e-59332e32fa59

Catalogue record

Date deposited: 05 Oct 2018 11:50
Last modified: 05 Oct 2018 11:50

Export record

Altmetrics

Contributors

Author: M. Siddiqui
Author: M. Chand
Author: C. Eng
Author: A. Mehdizadeh
Author: A. Mirnezami
Author: G. Brown

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×