Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology
Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology
Cerebral small vessel disease (SVD) is a major contributor to stroke, cognitive impairment and dementia with limited therapeutic interventions. There is a critical need to provide mechanistic insight and improve translation between pre-clinical research and the clinic. A 2-day workshop was held which brought together experts from several disciplines in cerebrovascular disease, dementia and cardiovascular biology, to highlight current advances in these fields, explore synergies and scope for development. These proceedings provide a summary of key talks at the workshop with a particular focus on animal models of cerebral vascular disease and dementia, mechanisms and approaches to improve translation. The outcomes of discussion groups on related themes to identify the gaps in knowledge and requirements to advance knowledge are summarized.
851-868
Horsburgh, Karen
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Wardlaw, Joanna M.
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van Agtmael, Tom
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Carare, Roxana O.
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Hawkes, Cheryl A.
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Horsburgh, Karen
1bba1a89-7a12-471f-b229-c3633e1a1a57
Wardlaw, Joanna M.
8e7202ad-0fd9-430c-b26a-05b1106ecaad
van Agtmael, Tom
82ad1f75-4a91-41d2-93e3-dd5eaaed7479
Carare, Roxana O.
0478c197-b0c1-4206-acae-54e88c8f21fa
Hawkes, Cheryl A.
031a17ac-0931-4ff9-93cc-df8cb58e14f7
et al.
(2018)
Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.
Clinical Science, 132 (8), .
(doi:10.1042/CS20171620).
Abstract
Cerebral small vessel disease (SVD) is a major contributor to stroke, cognitive impairment and dementia with limited therapeutic interventions. There is a critical need to provide mechanistic insight and improve translation between pre-clinical research and the clinic. A 2-day workshop was held which brought together experts from several disciplines in cerebrovascular disease, dementia and cardiovascular biology, to highlight current advances in these fields, explore synergies and scope for development. These proceedings provide a summary of key talks at the workshop with a particular focus on animal models of cerebral vascular disease and dementia, mechanisms and approaches to improve translation. The outcomes of discussion groups on related themes to identify the gaps in knowledge and requirements to advance knowledge are summarized.
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Accepted/In Press date: 21 February 2018
e-pub ahead of print date: 30 April 2018
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Local EPrints ID: 424880
URI: http://eprints.soton.ac.uk/id/eprint/424880
ISSN: 0143-5221
PURE UUID: bd2bdcec-80fc-4d8e-ae3b-bd4302f73f4e
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Date deposited: 05 Oct 2018 11:52
Last modified: 06 Jun 2024 01:37
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Author:
Karen Horsburgh
Author:
Joanna M. Wardlaw
Author:
Tom van Agtmael
Author:
Cheryl A. Hawkes
Corporate Author: et al.
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