Recurrent acute pancreatitis: International state-of-the-science conference with recommendations
Recurrent acute pancreatitis: International state-of-the-science conference with recommendations
Recurrent acute pancreatitis (RAP) is a clinically significant problem globally. The etiology remains unclear in approximately 10% to 15% of patients despite a thorough workup. Data on natural history and efficacy of treatments are limited. We aimed to establish criteria for diagnosis, evaluate the causative factors, and arrive at a consensus on the appropriate workup and management of patients with RAP. The organizing committee was formed, and a set of questions was developed based on the current evidence, controversies, and topics that needed further research. After a vetting process, these topics were assigned to a group of experts from around the world with special interest in RAP. Data were presented as part of a workshop on RAP organized as a part of the annual meeting of the America Pancreatic Association. Pretest and Posttest questions were administered, and the responses were tabulated by the current Grades of Recommendation Assessment, Development and Evaluation system. The consensus guidelines were established in the format of a diagnostic algorithm. Several deficiencies were identified with respect to data on etiology, treatment efficacies, and areas that need immediate research.
diagnostic algorithm, etiology, recurrent acute pancreatitis, treatment efficacies, workup
653-666
Guda, Nalini M.
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Muddana, Venkata
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Whitcomb, David C.
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Levy, Philippe
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Garg, Pramod
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Cote, Gregory
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Uc, Aliye
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Varadarajulu, Shyam
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Vege, Santhi S.
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Chari, Suresh T.
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Forsmark, Chris E.
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Yadav, Dhiraj
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Reddy, D. Nageshwar
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Tenner, Scott
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Johnson, Colin D.
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Akisik, Fatih
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Saluja, Ashok K.
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Lerch, Markus M.
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Mallery, J. Shawn
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Freeman, Martin L.
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1 July 2018
Guda, Nalini M.
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Muddana, Venkata
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Whitcomb, David C.
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Levy, Philippe
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Garg, Pramod
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Cote, Gregory
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Uc, Aliye
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Varadarajulu, Shyam
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Vege, Santhi S.
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Chari, Suresh T.
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Forsmark, Chris E.
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Yadav, Dhiraj
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Reddy, D. Nageshwar
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Tenner, Scott
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Johnson, Colin D.
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Akisik, Fatih
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Saluja, Ashok K.
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Lerch, Markus M.
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Mallery, J. Shawn
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Freeman, Martin L.
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Guda, Nalini M., Muddana, Venkata, Whitcomb, David C., Levy, Philippe, Garg, Pramod, Cote, Gregory, Uc, Aliye, Varadarajulu, Shyam, Vege, Santhi S., Chari, Suresh T., Forsmark, Chris E., Yadav, Dhiraj, Reddy, D. Nageshwar, Tenner, Scott, Johnson, Colin D., Akisik, Fatih, Saluja, Ashok K., Lerch, Markus M., Mallery, J. Shawn and Freeman, Martin L.
(2018)
Recurrent acute pancreatitis: International state-of-the-science conference with recommendations.
Pancreas, 47 (6), .
(doi:10.1097/MPA.0000000000001053).
Abstract
Recurrent acute pancreatitis (RAP) is a clinically significant problem globally. The etiology remains unclear in approximately 10% to 15% of patients despite a thorough workup. Data on natural history and efficacy of treatments are limited. We aimed to establish criteria for diagnosis, evaluate the causative factors, and arrive at a consensus on the appropriate workup and management of patients with RAP. The organizing committee was formed, and a set of questions was developed based on the current evidence, controversies, and topics that needed further research. After a vetting process, these topics were assigned to a group of experts from around the world with special interest in RAP. Data were presented as part of a workshop on RAP organized as a part of the annual meeting of the America Pancreatic Association. Pretest and Posttest questions were administered, and the responses were tabulated by the current Grades of Recommendation Assessment, Development and Evaluation system. The consensus guidelines were established in the format of a diagnostic algorithm. Several deficiencies were identified with respect to data on etiology, treatment efficacies, and areas that need immediate research.
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More information
Accepted/In Press date: 2 March 2018
Published date: 1 July 2018
Keywords:
diagnostic algorithm, etiology, recurrent acute pancreatitis, treatment efficacies, workup
Identifiers
Local EPrints ID: 424955
URI: http://eprints.soton.ac.uk/id/eprint/424955
ISSN: 0885-3177
PURE UUID: 5ca7e7de-6c93-4d18-b079-b27201c28365
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Date deposited: 05 Oct 2018 16:30
Last modified: 15 Mar 2024 20:49
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Contributors
Author:
Nalini M. Guda
Author:
Venkata Muddana
Author:
David C. Whitcomb
Author:
Philippe Levy
Author:
Pramod Garg
Author:
Gregory Cote
Author:
Aliye Uc
Author:
Shyam Varadarajulu
Author:
Santhi S. Vege
Author:
Suresh T. Chari
Author:
Chris E. Forsmark
Author:
Dhiraj Yadav
Author:
D. Nageshwar Reddy
Author:
Scott Tenner
Author:
Fatih Akisik
Author:
Ashok K. Saluja
Author:
Markus M. Lerch
Author:
J. Shawn Mallery
Author:
Martin L. Freeman
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