Identifying individuals with chronic pain after knee replacement: A population-cohort, cluster-analysis of Oxford knee scores in 128,145 patients from the English National Health Service 11 Medical and Health Sciences 1103 Clinical Sciences
Identifying individuals with chronic pain after knee replacement: A population-cohort, cluster-analysis of Oxford knee scores in 128,145 patients from the English National Health Service 11 Medical and Health Sciences 1103 Clinical Sciences
Background: Approximately one in five patients undergoing knee replacement surgery experience chronic pain after their operation, which can negatively impact on their quality of life. In order to develop and evaluate interventions to improve the management of chronic post-surgical pain, we aimed to derive a cut-off point in the Oxford Knee Score pain subscale to identify patients with chronic pain following knee replacement, and to characterise these patients using self-reported outcomes. Methods: Data from the English Patient-Reported Outcome Measures (PROMs) programme were used. This comprised patient-reported data from 128,145 patients who underwent primary knee replacement surgery in England between 2012 and 2015. Cluster analysis was applied to derive a cut-off point on the pain subscale of the Oxford Knee Score. Results: A high-pain group was identified, described by a maximum of 14 points in the Oxford Knee Score pain subscale six months after surgery. The high-pain group, comprising 15% of the sample, was characterised by severe and frequent problems in all pain dimensions, particularly in pain severity, night pain and limping, as well as in all dimensions of health-related quality of life. Conclusions: Patients with Oxford Knee Score pain subscale scores of 14 or less at six months after knee replacement can be considered to be in chronic pain that is likely to negatively affect their quality of life. This derived cut-off can be used for patient selection in research settings to design and assess interventions that support patients in their management of chronic post-surgical pain.
Chronic pain, Cluster-analysis, Knee replacement, NHS England, Observational study, Oxford knee score
Pinedo-Villanueva, Rafael
7375e99b-3bac-4210-841e-ec4724df9131
Khalid, Sara
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Wylde, Vikki
61bf727a-db51-49ba-ac21-96612a692cbc
Gooberman-Hill, Rachael
7464450e-287b-4f00-bc64-21a3fcba88a6
Soni, Anushka
5b9827c7-be82-42cf-b7d3-707d73c6da5a
Judge, Andrew
b853f89f-dc44-428e-9fe2-35e925544abe
2 October 2018
Pinedo-Villanueva, Rafael
7375e99b-3bac-4210-841e-ec4724df9131
Khalid, Sara
e86b1286-c1a9-40c1-aa80-c62ceb4c92d9
Wylde, Vikki
61bf727a-db51-49ba-ac21-96612a692cbc
Gooberman-Hill, Rachael
7464450e-287b-4f00-bc64-21a3fcba88a6
Soni, Anushka
5b9827c7-be82-42cf-b7d3-707d73c6da5a
Judge, Andrew
b853f89f-dc44-428e-9fe2-35e925544abe
Pinedo-Villanueva, Rafael, Khalid, Sara, Wylde, Vikki, Gooberman-Hill, Rachael, Soni, Anushka and Judge, Andrew
(2018)
Identifying individuals with chronic pain after knee replacement: A population-cohort, cluster-analysis of Oxford knee scores in 128,145 patients from the English National Health Service 11 Medical and Health Sciences 1103 Clinical Sciences.
BMC Musculoskeletal Disorders, 19 (1), [354].
(doi:10.1186/s12891-018-2270-9).
Abstract
Background: Approximately one in five patients undergoing knee replacement surgery experience chronic pain after their operation, which can negatively impact on their quality of life. In order to develop and evaluate interventions to improve the management of chronic post-surgical pain, we aimed to derive a cut-off point in the Oxford Knee Score pain subscale to identify patients with chronic pain following knee replacement, and to characterise these patients using self-reported outcomes. Methods: Data from the English Patient-Reported Outcome Measures (PROMs) programme were used. This comprised patient-reported data from 128,145 patients who underwent primary knee replacement surgery in England between 2012 and 2015. Cluster analysis was applied to derive a cut-off point on the pain subscale of the Oxford Knee Score. Results: A high-pain group was identified, described by a maximum of 14 points in the Oxford Knee Score pain subscale six months after surgery. The high-pain group, comprising 15% of the sample, was characterised by severe and frequent problems in all pain dimensions, particularly in pain severity, night pain and limping, as well as in all dimensions of health-related quality of life. Conclusions: Patients with Oxford Knee Score pain subscale scores of 14 or less at six months after knee replacement can be considered to be in chronic pain that is likely to negatively affect their quality of life. This derived cut-off can be used for patient selection in research settings to design and assess interventions that support patients in their management of chronic post-surgical pain.
Text
s12891-018-2270-9
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Accepted/In Press date: 20 September 2018
e-pub ahead of print date: 2 October 2018
Published date: 2 October 2018
Keywords:
Chronic pain, Cluster-analysis, Knee replacement, NHS England, Observational study, Oxford knee score
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Local EPrints ID: 425411
URI: http://eprints.soton.ac.uk/id/eprint/425411
PURE UUID: 5be034ac-4934-41d6-b5db-096b4432547e
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Date deposited: 18 Oct 2018 16:30
Last modified: 15 Mar 2024 22:12
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Contributors
Author:
Rafael Pinedo-Villanueva
Author:
Sara Khalid
Author:
Vikki Wylde
Author:
Rachael Gooberman-Hill
Author:
Anushka Soni
Author:
Andrew Judge
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