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A brief history of FRAX

A brief history of FRAX
A brief history of FRAX
Summary:

This paper reviews the research programme that went into the development of FRAX® and its impact in the 10 years since its release in 2008.

Introduction:

Osteoporosis is defined on the measurement of bone mineral density though the clinical consequence is fracture. The sensitivity of bone mineral density measurements for fracture prediction is low, leading to the development of FRAX to better calculate the likelihood of fracture and target anti-osteoporosis treatments.

Methods:

The method used in this paper is literature review.

Results:

FRAX, developed over an 8-year period, was launched in 2008. Since the launch of FRAX, models have been made available for 64 countries and in 31 languages covering more than 80% of the world population.

Conclusion:

FRAX provides an advance in fracture risk assessment and a reference technology platform for future improvements in performance characteristics.
1862-3522
Kanis, J A.
55c6bd2c-d653-48de-b4b9-29fe280fb00f
Johansson, H.
05aa5476-bcb9-4b97-905e-00f1dfd9d691
Harvey, N.C.
ce487fb4-d360-4aac-9d17-9466d6cba145
McCloskey, E. V.
e968a69f-27b8-4568-987d-5d8dbbdff3fd
Kanis, J A.
55c6bd2c-d653-48de-b4b9-29fe280fb00f
Johansson, H.
05aa5476-bcb9-4b97-905e-00f1dfd9d691
Harvey, N.C.
ce487fb4-d360-4aac-9d17-9466d6cba145
McCloskey, E. V.
e968a69f-27b8-4568-987d-5d8dbbdff3fd

Kanis, J A., Johansson, H., Harvey, N.C. and McCloskey, E. V. (2018) A brief history of FRAX. Archives of Osteoporosis, 13 (118). (doi:10.1007/s11657-018-0510-0).

Record type: Article

Abstract

Summary:

This paper reviews the research programme that went into the development of FRAX® and its impact in the 10 years since its release in 2008.

Introduction:

Osteoporosis is defined on the measurement of bone mineral density though the clinical consequence is fracture. The sensitivity of bone mineral density measurements for fracture prediction is low, leading to the development of FRAX to better calculate the likelihood of fracture and target anti-osteoporosis treatments.

Methods:

The method used in this paper is literature review.

Results:

FRAX, developed over an 8-year period, was launched in 2008. Since the launch of FRAX, models have been made available for 64 countries and in 31 languages covering more than 80% of the world population.

Conclusion:

FRAX provides an advance in fracture risk assessment and a reference technology platform for future improvements in performance characteristics.

Text
A brief history of FRAX v5 - Accepted Manuscript
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More information

Accepted/In Press date: 19 August 2018
e-pub ahead of print date: 31 October 2018
Published date: December 2018

Identifiers

Local EPrints ID: 426039
URI: https://eprints.soton.ac.uk/id/eprint/426039
ISSN: 1862-3522
PURE UUID: 1e6f23e3-149d-4b42-98a6-71b512d08235
ORCID for N.C. Harvey: ORCID iD orcid.org/0000-0002-8194-2512

Catalogue record

Date deposited: 09 Nov 2018 17:30
Last modified: 10 Dec 2019 05:09

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Contributors

Author: J A. Kanis
Author: H. Johansson
Author: N.C. Harvey ORCID iD
Author: E. V. McCloskey

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