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Field-cycling long-lived-state NMR of 15N2 spin pairs

Field-cycling long-lived-state NMR of 15N2 spin pairs
Field-cycling long-lived-state NMR of 15N2 spin pairs
A range of nuclear magnetic resonance spectroscopy and imaging applications are limited by the short lifetimes of magnetisation in solution. Long-lived states, which are slowly relaxing configurations of nuclear spins, have been shown to alleviate this limitation. Long-lived states have decay lifetimes significantly exceeding the longitudinal relaxation time , in some cases by an order of magnitude. Here we present an experimental case of a long-lived state for a 15N labelled molecular system in solution. We observe a strongly biexponential decay for the long-lived state, with the lifetime of the slowly relaxing component exceeding 40 minutes, ∼21 times longer than the spin-lattice relaxation time . The lifetime of the long-lived state was revealed by using a dedicated two-field NMR spectrometer capable of fast sample shuttling between high and low magnetic fields, and the application of a resonant radiofrequency field at low magnetic field. The relaxation characteristics of the long-lived state are examined.
0026-8976
1-8
Elliott, Stuart J
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Kadeřávek, Pavel
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Brown, Lynda J.
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Sabba, Mohamed
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Gloggler, Stefan
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O'Leary, Daniel J.
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Brown, Richard C.D.
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Ferrage, Fabien
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Levitt, Malcolm H.
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Elliott, Stuart J
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Kadeřávek, Pavel
b3077f38-8af7-469b-9c03-b7738464e3a5
Brown, Lynda J.
75aa95fa-5d27-46a7-9dbe-0f465a664f5b
Sabba, Mohamed
86002c7a-3fb8-4629-a13b-fbd6737b3c46
Gloggler, Stefan
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O'Leary, Daniel J.
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Brown, Richard C.D.
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Ferrage, Fabien
51c177eb-7bb9-4362-b148-4adc65acd74d
Levitt, Malcolm H.
bcc5a80a-e5c5-4e0e-9a9a-249d036747c3

Elliott, Stuart J, Kadeřávek, Pavel, Brown, Lynda J., Sabba, Mohamed, Gloggler, Stefan, O'Leary, Daniel J., Brown, Richard C.D., Ferrage, Fabien and Levitt, Malcolm H. (2018) Field-cycling long-lived-state NMR of 15N2 spin pairs. Molecular Physics, 1-8. (doi:10.1080/00268976.2018.1543906).

Record type: Article

Abstract

A range of nuclear magnetic resonance spectroscopy and imaging applications are limited by the short lifetimes of magnetisation in solution. Long-lived states, which are slowly relaxing configurations of nuclear spins, have been shown to alleviate this limitation. Long-lived states have decay lifetimes significantly exceeding the longitudinal relaxation time , in some cases by an order of magnitude. Here we present an experimental case of a long-lived state for a 15N labelled molecular system in solution. We observe a strongly biexponential decay for the long-lived state, with the lifetime of the slowly relaxing component exceeding 40 minutes, ∼21 times longer than the spin-lattice relaxation time . The lifetime of the long-lived state was revealed by using a dedicated two-field NMR spectrometer capable of fast sample shuttling between high and low magnetic fields, and the application of a resonant radiofrequency field at low magnetic field. The relaxation characteristics of the long-lived state are examined.

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SJE-15N2-V9 - Accepted Manuscript
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Accepted/In Press date: 12 October 2018
e-pub ahead of print date: 8 November 2018

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Local EPrints ID: 426230
URI: http://eprints.soton.ac.uk/id/eprint/426230
ISSN: 0026-8976
PURE UUID: aa1c65c5-783a-4757-ad30-31ad98e9472d
ORCID for Lynda J. Brown: ORCID iD orcid.org/0000-0002-5678-0814
ORCID for Richard C.D. Brown: ORCID iD orcid.org/0000-0003-0156-7087
ORCID for Malcolm H. Levitt: ORCID iD orcid.org/0000-0001-9878-1180

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Date deposited: 20 Nov 2018 17:30
Last modified: 15 Sep 2021 04:09

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Contributors

Author: Stuart J Elliott
Author: Pavel Kadeřávek
Author: Lynda J. Brown ORCID iD
Author: Mohamed Sabba
Author: Stefan Gloggler
Author: Daniel J. O'Leary
Author: Fabien Ferrage

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