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MRI based 3D finite element modelling to investigate deep tissue injury

MRI based 3D finite element modelling to investigate deep tissue injury
MRI based 3D finite element modelling to investigate deep tissue injury

Pressure ulcers occur due to sustained mechanical loading. Deep tissue injury is a severe type of pressure ulcer, which is believed to originate in subcutaneous tissues adjacent to bony prominences. In previous experimental-numerical studies the relationship between internal tissue state and damage development was investigated using a 2D analysis. However, recent studies suggest that a local analysis is not sufficient. In the present study we developed a method to create animal-specific 3D finite element models of an indentation test on the tibialis anterior muscle of rats based on MRI data. A detailed description on how the animal specific models are created is given. Furthermore, two indenter geometries are compared and the influence of errors in determining the indenter orientation on the resulting internal strain distribution in a defined volume of tissue was investigated. We conclude that with a spherically-shaped indenter errors in estimating the indenter orientation do not unduly influence the results of the simulation.

deep tissue injury, finite element modelling (FE), indentation test, magnetic resonance imaging (MRI), pressure ulcer
1025-5842
1-10
Traa, Willeke A.
7133843c-25e6-456b-b472-a70e15ba9f28
van Turnhout, Mark C.
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Moerman, Kevin M.
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Nelissen, Jules L.
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Nederveen, Aart J.
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Strijkers, Gustav J.
c8506691-27fd-48f5-9ba9-174ba3feed28
Bader, Dan L.
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Oomens, Cees W.J.
b4884336-5230-4055-9df2-5400c1c57018
Traa, Willeke A.
7133843c-25e6-456b-b472-a70e15ba9f28
van Turnhout, Mark C.
99444db0-dd4d-4bb1-9cd0-966eb9d5aba9
Moerman, Kevin M.
a60ced26-e166-49aa-a10c-85e1018118c9
Nelissen, Jules L.
d7ade1c4-43ea-4331-b623-67d229300720
Nederveen, Aart J.
f0c91a07-4255-47eb-9760-cfd880aaeae0
Strijkers, Gustav J.
c8506691-27fd-48f5-9ba9-174ba3feed28
Bader, Dan L.
9884d4f6-2607-4d48-bf0c-62bdcc0d1dbf
Oomens, Cees W.J.
b4884336-5230-4055-9df2-5400c1c57018

Traa, Willeke A., van Turnhout, Mark C., Moerman, Kevin M., Nelissen, Jules L., Nederveen, Aart J., Strijkers, Gustav J., Bader, Dan L. and Oomens, Cees W.J. (2018) MRI based 3D finite element modelling to investigate deep tissue injury. Computer Methods in Biomechanics and Biomedical Engineering, 1-10. (doi:10.1080/10255842.2018.1517868).

Record type: Article

Abstract

Pressure ulcers occur due to sustained mechanical loading. Deep tissue injury is a severe type of pressure ulcer, which is believed to originate in subcutaneous tissues adjacent to bony prominences. In previous experimental-numerical studies the relationship between internal tissue state and damage development was investigated using a 2D analysis. However, recent studies suggest that a local analysis is not sufficient. In the present study we developed a method to create animal-specific 3D finite element models of an indentation test on the tibialis anterior muscle of rats based on MRI data. A detailed description on how the animal specific models are created is given. Furthermore, two indenter geometries are compared and the influence of errors in determining the indenter orientation on the resulting internal strain distribution in a defined volume of tissue was investigated. We conclude that with a spherically-shaped indenter errors in estimating the indenter orientation do not unduly influence the results of the simulation.

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11-30-2018_MRI based - Version of Record
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More information

Accepted/In Press date: 27 August 2018
e-pub ahead of print date: 6 November 2018
Keywords: deep tissue injury, finite element modelling (FE), indentation test, magnetic resonance imaging (MRI), pressure ulcer

Identifiers

Local EPrints ID: 426544
URI: http://eprints.soton.ac.uk/id/eprint/426544
ISSN: 1025-5842
PURE UUID: 7813cf5d-76c3-45e8-a743-72ea461b5a88
ORCID for Dan L. Bader: ORCID iD orcid.org/0000-0002-1208-3507

Catalogue record

Date deposited: 30 Nov 2018 17:30
Last modified: 26 Nov 2021 02:57

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Contributors

Author: Willeke A. Traa
Author: Mark C. van Turnhout
Author: Kevin M. Moerman
Author: Jules L. Nelissen
Author: Aart J. Nederveen
Author: Gustav J. Strijkers
Author: Dan L. Bader ORCID iD
Author: Cees W.J. Oomens

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