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Does intra-uterine insemination have a place in modern ART practice?

Does intra-uterine insemination have a place in modern ART practice?
Does intra-uterine insemination have a place in modern ART practice?

Intra-uterine insemination (IUI) is a cheaper, less intensive treatment modality for achieving a pregnancy in couples with specific indications. The use of IUI seems to have declined after NICE guideline 2013 (CG 156) recommended IVF over IUI in couples with unexplained and mild male factor infertility. This review examines the current evidence and the applicability of IUI as a first-line option of treatment in couples with unexplained and mild male factor subfertility. The outcome of the review supports this argument. It is likely that IUI will re-emerge as an effective treatment option and thereby increase the choice to patients. However, there is a need for ongoing research and investment into funding of good quality trials to improve and strengthen the evidence base.

Intrauterine insemination (IUI), Mild male factor infertility, Ovarian stimulation, Unexplained infertility
1521-6934
3-10
Kandavel, Valarmathy
8486486e-3631-42c7-a906-8d7256bea930
Cheong, Ying
4efbba2a-3036-4dce-82f1-8b4017952c83
Kandavel, Valarmathy
8486486e-3631-42c7-a906-8d7256bea930
Cheong, Ying
4efbba2a-3036-4dce-82f1-8b4017952c83

Kandavel, Valarmathy and Cheong, Ying (2018) Does intra-uterine insemination have a place in modern ART practice? Best Practice & Research Clinical Obstetrics & Gynaecology, 53, 3-10. (doi:10.1016/j.bpobgyn.2018.08.003).

Record type: Review

Abstract

Intra-uterine insemination (IUI) is a cheaper, less intensive treatment modality for achieving a pregnancy in couples with specific indications. The use of IUI seems to have declined after NICE guideline 2013 (CG 156) recommended IVF over IUI in couples with unexplained and mild male factor infertility. This review examines the current evidence and the applicability of IUI as a first-line option of treatment in couples with unexplained and mild male factor subfertility. The outcome of the review supports this argument. It is likely that IUI will re-emerge as an effective treatment option and thereby increase the choice to patients. However, there is a need for ongoing research and investment into funding of good quality trials to improve and strengthen the evidence base.

Text
Does IUI have a place in modern ART practice Valar Oct 2018 - Accepted Manuscript
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More information

e-pub ahead of print date: 25 August 2018
Published date: November 2018
Additional Information: Copyright © 2018. Published by Elsevier Ltd.
Keywords: Intrauterine insemination (IUI), Mild male factor infertility, Ovarian stimulation, Unexplained infertility

Identifiers

Local EPrints ID: 426576
URI: https://eprints.soton.ac.uk/id/eprint/426576
ISSN: 1521-6934
PURE UUID: 85e46054-364b-4a9a-b313-4a5f08aaf278
ORCID for Ying Cheong: ORCID iD orcid.org/0000-0001-7687-4597

Catalogue record

Date deposited: 30 Nov 2018 17:30
Last modified: 25 Aug 2019 04:01

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