The authors reply: Letter on: "Pitfalls in the measurement of muscle mass: a need for a reference standard" by Clark et al
The authors reply: Letter on: "Pitfalls in the measurement of muscle mass: a need for a reference standard" by Clark et al
However, semantics aside, we think that DXA can indeed serve as a reference standard for measuring muscle mass. Obviously, CT and MRI are advanced techniques that can and have been used to obtain important information such as muscle size/volume and more recently amount and distribution of intra- and intermuscular adipose tissue. Also individual muscles can be assessed separately. However, with respect to muscle mass, the comparison of DXA with CT/MRI is rather difficult because DXA and QCT/MRI measure different physical parameters.
Lean body mass, Lean mass, Muscle mass, Reference standard
1272-1274
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Landi, Francesco
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Engelke, Klaus
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Maggi, Stefania
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Dennison, Elaine
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Al-Daghri, Nasser M.
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Allepaerts, Sophie
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Bauer, Jurgen
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Bautmans, Ivan
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Brandi, Maria Luisa
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Bruyère, Olivier
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Cooper, Cyrus
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Dawson-Hughes, Bess
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Laslop, Andrea
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Petermans, Jean
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Reginster, Jean Yves
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Rizzoli, René
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Robinson, Sian
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Rolland, Yves
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Rueda, Ricardo
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Vellas, Bruno
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Kanis, John A.
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