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Association of mitochondrial respiratory chain deficiency in older men with muscle mass and physical performance: findings from the Hertfordshire Sarcopenia Study

Association of mitochondrial respiratory chain deficiency in older men with muscle mass and physical performance: findings from the Hertfordshire Sarcopenia Study
Association of mitochondrial respiratory chain deficiency in older men with muscle mass and physical performance: findings from the Hertfordshire Sarcopenia Study
Sarcopenia has been defined as low muscle mass and physical performance, and recognition of its importance in clinical practice is growing. Declines in muscle mitochondrial function with age have been described although less is known about the role of mitochondrial dysfunction in sarcopenia. The aim of this study was to investigate whether respiratory chain deficiency is associated with muscle mass and physical performance.
0140-6736
S87
Rygiel, Karolina
70f76c81-a29a-4ba6-bab5-970ad0657eb5
Dodds, Richard
dda3190c-1273-43ca-b440-109f2cdf301b
Patel, Harnish
514aba46-4dc9-4011-b393-ce83c6206754
Syddall, Holly
333a7102-653a-4391-a6b5-cb78cb33bc93
Westbury, Leo
5ed45df3-3df7-4bf9-bbad-07b63cd4b281
Granic, Antoneta
68bdeb08-01a4-45a8-9b87-7a8728d4c3fa
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Cliff, Joshua
350f2dfd-6db4-486a-b66d-2caab01055a9
Rocha, Mariana
bb1c94ad-ac49-49a5-8b93-48af76ef8fb5
Turnbull, Doug
d0cc7296-a1e3-4ab9-b97c-2b785cf12361
Sayer, Avan
a85472e7-8894-44b2-913f-cd77e96895db
Rygiel, Karolina
70f76c81-a29a-4ba6-bab5-970ad0657eb5
Dodds, Richard
dda3190c-1273-43ca-b440-109f2cdf301b
Patel, Harnish
514aba46-4dc9-4011-b393-ce83c6206754
Syddall, Holly
333a7102-653a-4391-a6b5-cb78cb33bc93
Westbury, Leo
5ed45df3-3df7-4bf9-bbad-07b63cd4b281
Granic, Antoneta
68bdeb08-01a4-45a8-9b87-7a8728d4c3fa
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Cliff, Joshua
350f2dfd-6db4-486a-b66d-2caab01055a9
Rocha, Mariana
bb1c94ad-ac49-49a5-8b93-48af76ef8fb5
Turnbull, Doug
d0cc7296-a1e3-4ab9-b97c-2b785cf12361
Sayer, Avan
a85472e7-8894-44b2-913f-cd77e96895db

Rygiel, Karolina, Dodds, Richard, Patel, Harnish, Syddall, Holly, Westbury, Leo, Granic, Antoneta, Cooper, Cyrus, Cliff, Joshua, Rocha, Mariana, Turnbull, Doug and Sayer, Avan (2017) Association of mitochondrial respiratory chain deficiency in older men with muscle mass and physical performance: findings from the Hertfordshire Sarcopenia Study. The Lancet, 389 (Supplement 1), S87. (doi:10.1016/S0140-6736(17)30483-X).

Record type: Meeting abstract

Abstract

Sarcopenia has been defined as low muscle mass and physical performance, and recognition of its importance in clinical practice is growing. Declines in muscle mitochondrial function with age have been described although less is known about the role of mitochondrial dysfunction in sarcopenia. The aim of this study was to investigate whether respiratory chain deficiency is associated with muscle mass and physical performance.

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e-pub ahead of print date: 23 February 2017

Identifiers

Local EPrints ID: 429194
URI: http://eprints.soton.ac.uk/id/eprint/429194
ISSN: 0140-6736
PURE UUID: 1fa303f7-95e1-4ffc-960d-b8f944f0c8a7
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 22 Mar 2019 17:30
Last modified: 23 Mar 2019 01:36

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Contributors

Author: Karolina Rygiel
Author: Richard Dodds
Author: Harnish Patel
Author: Holly Syddall
Author: Leo Westbury
Author: Antoneta Granic
Author: Cyrus Cooper ORCID iD
Author: Joshua Cliff
Author: Mariana Rocha
Author: Doug Turnbull
Author: Avan Sayer

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