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Innate immunity: A new chapter for hepatitis C

Innate immunity: A new chapter for hepatitis C
Innate immunity: A new chapter for hepatitis C
The immune response to hepatitis C virus (HCV) and the mechanisms leading to successful
resolution are complex. Much work has been done on understanding the adaptive immune
response to HCV due to the imperative of trying to find a vaccine. However the importance
of the innate immune system is being increasingly recognized. This has culminated in the discovery of IL-28B as a key genetic element in recovery from HCV in diverse populations.
This association is one of the strongest in anti-viral immunity and represents a paradigm shift
in how we view the immune response to HCV infection.
1108-7471
232-240
Hydes, Theresa
d842d1ec-c64a-4934-a5a2-7316fea65767
Khakoo, Salim
6c16d2f5-ae80-4d9b-9100-6bfb34ad0273
Hydes, Theresa
d842d1ec-c64a-4934-a5a2-7316fea65767
Khakoo, Salim
6c16d2f5-ae80-4d9b-9100-6bfb34ad0273

Hydes, Theresa and Khakoo, Salim (2012) Innate immunity: A new chapter for hepatitis C. Annals of Gastroenterology, 25 (3), 232-240.

Record type: Article

Abstract

The immune response to hepatitis C virus (HCV) and the mechanisms leading to successful
resolution are complex. Much work has been done on understanding the adaptive immune
response to HCV due to the imperative of trying to find a vaccine. However the importance
of the innate immune system is being increasingly recognized. This has culminated in the discovery of IL-28B as a key genetic element in recovery from HCV in diverse populations.
This association is one of the strongest in anti-viral immunity and represents a paradigm shift
in how we view the immune response to HCV infection.

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Published date: 2012
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Identifiers

Local EPrints ID: 429198
URI: http://eprints.soton.ac.uk/id/eprint/429198
ISSN: 1108-7471
PURE UUID: ddae450f-874b-46a6-b3d1-06ca4651b095
ORCID for Salim Khakoo: ORCID iD orcid.org/0000-0002-4057-9091

Catalogue record

Date deposited: 22 Mar 2019 17:30
Last modified: 16 Mar 2024 03:25

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Contributors

Author: Theresa Hydes
Author: Salim Khakoo ORCID iD

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