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A national survey of the provision of ultrasound surveillance for the detection of hepatocellular carcinoma

A national survey of the provision of ultrasound surveillance for the detection of hepatocellular carcinoma
A national survey of the provision of ultrasound surveillance for the detection of hepatocellular carcinoma
Objective Hepatocellular carcinoma (HCC), the sixth most common cancer worldwide and third most common cause of cancer related death, is closely associated with the presence of cirrhosis. Survival is determined by the stage of the cancer, with asymptomatic small tumours being more amenable to treatment. Early diagnosis is dependent on regular surveillance and the primary objective of this survey was to gain a better understanding of the baseline attitudes towards and provision of ultrasound surveillance (USS) HCC surveillance in the UK. In addition, information was obtained on the stages of cancer of the patients being referred to and discussed at regional multidisciplinary team meetings.

Design UK hepatologists, gastroenterologists and nurse specialists were sent a questionnaire survey regarding the provision of USS for detection of HCC in their respective hospitals.

Results Provision of surveillance was poor overall, with many hospitals lacking the necessary mechanisms to make abnormal results, if detected, known to referring clinicians. There was also a lack of standard data collection and in many hospitals basic information on the number of patients with cirrhosis and how many were developing HCC was not known. For the majority of new HCC cases was currently being made only at an incurable late stage (60%).

Conclusions In the UK, the current provision of USS based HCC surveillance is poor and needs to be upgraded urgently.
2041-4137
82-89
Cross, T.J.S.
341319a8-76e1-4e83-aad8-59a0f96c6f83
Villaneuva, A.
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Shetty, S.
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Wilkes, E.
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Collins, P.
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Adair, A.
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Jones, R.L.
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Foxton, M.R.
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Meyer, T.
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Stern, N.
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Warshow, U.
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Khan, N.
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Prince, M.
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Khakoo, S.
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Alexander, G.J.
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Khan, S.
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Reeves, H.
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Marshall, Aileen
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Williams, R.
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Cross, T.J.S.
341319a8-76e1-4e83-aad8-59a0f96c6f83
Villaneuva, A.
9abd528e-c337-431d-b4ca-996151b0da8e
Shetty, S.
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Wilkes, E.
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Collins, P.
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Adair, A.
da40c639-52f1-4409-953c-b772cf0b0093
Jones, R.L.
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Foxton, M.R.
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Meyer, T.
8ac918a9-e659-4d8e-8ada-7c0b205b54e6
Stern, N.
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Warshow, U.
91ef0fd3-2fa9-4d5b-ade0-0b84df0656e2
Khan, N.
e5cc5664-1e3d-44a5-9508-5d6be725af87
Prince, M.
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Khakoo, S.
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Alexander, G.J.
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Khan, S.
0afabaf7-e0d0-48e0-851c-5745639bdfc2
Reeves, H.
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Marshall, Aileen
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Williams, R.
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Cross, T.J.S., Villaneuva, A., Shetty, S., Wilkes, E., Collins, P., Adair, A., Jones, R.L., Foxton, M.R., Meyer, T., Stern, N., Warshow, U., Khan, N., Prince, M., Khakoo, S., Alexander, G.J., Khan, S., Reeves, H., Marshall, Aileen and Williams, R. (2015) A national survey of the provision of ultrasound surveillance for the detection of hepatocellular carcinoma. Frontline Gastroenterology, 7, 82-89. (doi:10.1136/flgastro-2015-100617).

Record type: Article

Abstract

Objective Hepatocellular carcinoma (HCC), the sixth most common cancer worldwide and third most common cause of cancer related death, is closely associated with the presence of cirrhosis. Survival is determined by the stage of the cancer, with asymptomatic small tumours being more amenable to treatment. Early diagnosis is dependent on regular surveillance and the primary objective of this survey was to gain a better understanding of the baseline attitudes towards and provision of ultrasound surveillance (USS) HCC surveillance in the UK. In addition, information was obtained on the stages of cancer of the patients being referred to and discussed at regional multidisciplinary team meetings.

Design UK hepatologists, gastroenterologists and nurse specialists were sent a questionnaire survey regarding the provision of USS for detection of HCC in their respective hospitals.

Results Provision of surveillance was poor overall, with many hospitals lacking the necessary mechanisms to make abnormal results, if detected, known to referring clinicians. There was also a lack of standard data collection and in many hospitals basic information on the number of patients with cirrhosis and how many were developing HCC was not known. For the majority of new HCC cases was currently being made only at an incurable late stage (60%).

Conclusions In the UK, the current provision of USS based HCC surveillance is poor and needs to be upgraded urgently.

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More information

Accepted/In Press date: 11 September 2015
e-pub ahead of print date: 7 December 2015

Identifiers

Local EPrints ID: 429199
URI: http://eprints.soton.ac.uk/id/eprint/429199
ISSN: 2041-4137
PURE UUID: d2fb15ef-482f-4887-8f96-32eaed706373

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Date deposited: 22 Mar 2019 17:30
Last modified: 09 Nov 2021 15:10

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Contributors

Author: T.J.S. Cross
Author: A. Villaneuva
Author: S. Shetty
Author: E. Wilkes
Author: P. Collins
Author: A. Adair
Author: R.L. Jones
Author: M.R. Foxton
Author: T. Meyer
Author: N. Stern
Author: U. Warshow
Author: N. Khan
Author: M. Prince
Author: S. Khakoo
Author: G.J. Alexander
Author: S. Khan
Author: H. Reeves
Author: Aileen Marshall
Author: R. Williams

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