The University of Southampton
University of Southampton Institutional Repository

Impact of osteoarthritis on activities of daily living: does joint site matter?

Impact of osteoarthritis on activities of daily living: does joint site matter?
Impact of osteoarthritis on activities of daily living: does joint site matter?
Background: we consider the relationships between a clinical and radiological diagnosis of knee or hip OA and activities of daily-living (ADL) in older adults.Methods: data were available for 222 men and 221 women from the Hertfordshire Cohort Study (HCS) who also participated in the UK component of the European Project on Osteoarthritis (EPOSA). Participants completed the EuroQoL survey where they reported if they had difficulties with mobility, self-care, usual activities and movement around their house. Hip and knee radiographs were graded for overall Kellgren and Lawrence score (positive definition defined as a 2 or above). Clinical OA was defined using American College of Rheumatology criteria.Results: in men, a clinical diagnosis of hip or knee OA were both associated with reported difficulties in mobility, ability to self-care and performing usual-activities (hip OA: OR 17.6, 95% CI 2.07, 149, p = 0.009; OR 12.5, 95% CI 2.51, 62.3, p = 0.002; OR 4.92, 95% CI 1.06, 22.8, p = 0.042 respectively. Knee OA: OR 8.18, 95% CI 3.32, 20.2, p < 0.001; OR 4.29, 95% CI 1.34, 13.7, p = 0.014; OR 5.32, 95% CI 2.26, 12.5, p < 0.001 respectively). Similar relationships were seen in women, where in addition, a radiological diagnosis of knee OA was associated with difficulties performing usual activities (OR 3.25, 95% CI 1.61, 6.54, p = 0.001). In general, men with OA reported stronger associations between moving around the house, specifically around the kitchen (clinical hip OA: OR 13.7, 95% CI 2.20, 85.6, p = 0.005; clinical knee OA OR 8.45, 95% CI 1.97, 36.2, p = 0.004) than women.Discussion and conclusion: clinical OA is strongly related to the ability to undertake ADL in older adults and should be considered in clinic consultations when seeing patients with OA.
1594-0667
1049–1056
Clynes, Michael
b860d3b7-12ee-42b8-8cd5-1e1abfccbee2
Jameson, Karen
d5fb142d-06af-456e-9016-17497f94e9f2
Edwards, Mark
b81ff294-1d16-4a1b-af14-9374c5989d4c
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Clynes, Michael
b860d3b7-12ee-42b8-8cd5-1e1abfccbee2
Jameson, Karen
d5fb142d-06af-456e-9016-17497f94e9f2
Edwards, Mark
b81ff294-1d16-4a1b-af14-9374c5989d4c
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1

Clynes, Michael, Jameson, Karen, Edwards, Mark, Cooper, Cyrus and Dennison, Elaine (2019) Impact of osteoarthritis on activities of daily living: does joint site matter? Aging Clinical and Experimental Research, 31 (8), 1049–1056. (doi:10.1007/s40520-019-01163-0).

Record type: Article

Abstract

Background: we consider the relationships between a clinical and radiological diagnosis of knee or hip OA and activities of daily-living (ADL) in older adults.Methods: data were available for 222 men and 221 women from the Hertfordshire Cohort Study (HCS) who also participated in the UK component of the European Project on Osteoarthritis (EPOSA). Participants completed the EuroQoL survey where they reported if they had difficulties with mobility, self-care, usual activities and movement around their house. Hip and knee radiographs were graded for overall Kellgren and Lawrence score (positive definition defined as a 2 or above). Clinical OA was defined using American College of Rheumatology criteria.Results: in men, a clinical diagnosis of hip or knee OA were both associated with reported difficulties in mobility, ability to self-care and performing usual-activities (hip OA: OR 17.6, 95% CI 2.07, 149, p = 0.009; OR 12.5, 95% CI 2.51, 62.3, p = 0.002; OR 4.92, 95% CI 1.06, 22.8, p = 0.042 respectively. Knee OA: OR 8.18, 95% CI 3.32, 20.2, p < 0.001; OR 4.29, 95% CI 1.34, 13.7, p = 0.014; OR 5.32, 95% CI 2.26, 12.5, p < 0.001 respectively). Similar relationships were seen in women, where in addition, a radiological diagnosis of knee OA was associated with difficulties performing usual activities (OR 3.25, 95% CI 1.61, 6.54, p = 0.001). In general, men with OA reported stronger associations between moving around the house, specifically around the kitchen (clinical hip OA: OR 13.7, 95% CI 2.20, 85.6, p = 0.005; clinical knee OA OR 8.45, 95% CI 1.97, 36.2, p = 0.004) than women.Discussion and conclusion: clinical OA is strongly related to the ability to undertake ADL in older adults and should be considered in clinic consultations when seeing patients with OA.

Text
Clynes et al manuscript ACER revised - Accepted Manuscript
Available under License Creative Commons Attribution.
Download (74kB)
Text
Clynes 2019 Article Impact of Osteoarthritis on Activities - Version of Record
Available under License Creative Commons Attribution.
Download (559kB)

More information

Accepted/In Press date: 27 February 2019
e-pub ahead of print date: 21 March 2019
Published date: August 2019

Identifiers

Local EPrints ID: 429635
URI: https://eprints.soton.ac.uk/id/eprint/429635
ISSN: 1594-0667
PURE UUID: f327666a-f2ea-4be9-80d1-9fa2acb68407
ORCID for Michael Clynes: ORCID iD orcid.org/0000-0001-7597-7658
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709
ORCID for Elaine Dennison: ORCID iD orcid.org/0000-0002-3048-4961

Catalogue record

Date deposited: 02 Apr 2019 16:30
Last modified: 10 Aug 2019 00:38

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×