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Destructive lesions in demyelinating disease

Destructive lesions in demyelinating disease
Destructive lesions in demyelinating disease

Three cases are presented in which clinical and radiological features suggested the diagnosis of glioma but surgical biopsy revealed a demyelinating process, with tissue destruction and cyst formation in two. One patient had clinically definite multiple sclerosis. Two had probable acute disseminated encephalomyelitis. Treatment with high dose steroids is appropriate when there is clinical or investigative evidence to suggest the presence of demyelinating disease, before deciding on biopsy.

0022-3050
288-292
Youl, B.D.
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Kermode, A.G.
4b319a3f-326a-45ad-a6a1-c653c3eab507
Thompson, A.J.
a3f53974-622e-4c37-b98b-41771a573dee
Revesz, T.
e5a3813b-4e1b-4846-a51f-838427820661
Scaravilli, F.
e208b359-04b3-482c-a6d3-a19859fae97a
Barnard, R.O.
2f3cf554-7a21-4d83-9b05-4910d5e10f45
Kirkham, F.J.
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58
Kendall, B.E.
f3bcbbb3-8fdd-4638-b9ff-3d946ebe178c
Kingsley, D.
6a257b05-9c0a-4d19-8233-f6de1dde4962
Moseley, I.F.
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Stevens, J.M.
e3cb3a09-ac98-47c9-b402-19dce3e4072e
Earl, C.J.
b0a30f28-d2d7-4087-b0a3-ae838b04bf29
McDonald, W.I.
11e6f52d-6ed2-40ef-90be-83493953fd52
Youl, B.D.
ea91ba2d-2712-41c1-ab92-5199128b384a
Kermode, A.G.
4b319a3f-326a-45ad-a6a1-c653c3eab507
Thompson, A.J.
a3f53974-622e-4c37-b98b-41771a573dee
Revesz, T.
e5a3813b-4e1b-4846-a51f-838427820661
Scaravilli, F.
e208b359-04b3-482c-a6d3-a19859fae97a
Barnard, R.O.
2f3cf554-7a21-4d83-9b05-4910d5e10f45
Kirkham, F.J.
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58
Kendall, B.E.
f3bcbbb3-8fdd-4638-b9ff-3d946ebe178c
Kingsley, D.
6a257b05-9c0a-4d19-8233-f6de1dde4962
Moseley, I.F.
e1c5e4a8-3e9e-4340-8fab-a1ac42c4ef1b
Stevens, J.M.
e3cb3a09-ac98-47c9-b402-19dce3e4072e
Earl, C.J.
b0a30f28-d2d7-4087-b0a3-ae838b04bf29
McDonald, W.I.
11e6f52d-6ed2-40ef-90be-83493953fd52

Youl, B.D., Kermode, A.G., Thompson, A.J., Revesz, T., Scaravilli, F., Barnard, R.O., Kirkham, F.J., Kendall, B.E., Kingsley, D., Moseley, I.F., Stevens, J.M., Earl, C.J. and McDonald, W.I. (1991) Destructive lesions in demyelinating disease. Journal of Neurology Neurosurgery and Psychiatry, 54 (4), 288-292. (doi:10.1136/jnnp.54.4.288).

Record type: Article

Abstract

Three cases are presented in which clinical and radiological features suggested the diagnosis of glioma but surgical biopsy revealed a demyelinating process, with tissue destruction and cyst formation in two. One patient had clinically definite multiple sclerosis. Two had probable acute disseminated encephalomyelitis. Treatment with high dose steroids is appropriate when there is clinical or investigative evidence to suggest the presence of demyelinating disease, before deciding on biopsy.

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Published date: April 1991

Identifiers

Local EPrints ID: 429773
URI: http://eprints.soton.ac.uk/id/eprint/429773
ISSN: 0022-3050
PURE UUID: 442621c3-ffd1-4cd3-9ffb-98de8f70a46c
ORCID for F.J. Kirkham: ORCID iD orcid.org/0000-0002-2443-7958

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Date deposited: 05 Apr 2019 16:30
Last modified: 23 Jul 2022 01:48

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Contributors

Author: B.D. Youl
Author: A.G. Kermode
Author: A.J. Thompson
Author: T. Revesz
Author: F. Scaravilli
Author: R.O. Barnard
Author: F.J. Kirkham ORCID iD
Author: B.E. Kendall
Author: D. Kingsley
Author: I.F. Moseley
Author: J.M. Stevens
Author: C.J. Earl
Author: W.I. McDonald

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