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Peripheral neuropathy and neuromuscular blockade presenting as prolonged respiratory paralysis following critical illness

Peripheral neuropathy and neuromuscular blockade presenting as prolonged respiratory paralysis following critical illness
Peripheral neuropathy and neuromuscular blockade presenting as prolonged respiratory paralysis following critical illness

We report two patients who following critical illness presented with generalised paralysis associated with persistent failure to breathe. Both patients eventually recovered and were weaned from the ventilator. The cause of the paralysis was an unusual peripheral neuropathy in the first patient and persistent neuromuscular blockade secondary to vecuronium in the second. It is important to consider a reversible, possibly even iatrogenic, cause of this type of complication.

Critical illness, Peripheral neuropathy, Prolonged neuromuscular blockade
0174-304X
123-125
Hechmatt, J.Z.
2a91e6df-54ad-462b-9ed4-7546f1f084b4
Pitt, M.C.
f078a02c-49f3-401e-bc66-4ba55b42bbb4
Kirkham, F.
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58
Hechmatt, J.Z.
2a91e6df-54ad-462b-9ed4-7546f1f084b4
Pitt, M.C.
f078a02c-49f3-401e-bc66-4ba55b42bbb4
Kirkham, F.
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58

Hechmatt, J.Z., Pitt, M.C. and Kirkham, F. (1993) Peripheral neuropathy and neuromuscular blockade presenting as prolonged respiratory paralysis following critical illness. Neuropediatrics, 24 (3), 123-125. (doi:10.1055/s-2008-1071527).

Record type: Article

Abstract

We report two patients who following critical illness presented with generalised paralysis associated with persistent failure to breathe. Both patients eventually recovered and were weaned from the ventilator. The cause of the paralysis was an unusual peripheral neuropathy in the first patient and persistent neuromuscular blockade secondary to vecuronium in the second. It is important to consider a reversible, possibly even iatrogenic, cause of this type of complication.

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More information

Published date: 1993
Keywords: Critical illness, Peripheral neuropathy, Prolonged neuromuscular blockade

Identifiers

Local EPrints ID: 429781
URI: http://eprints.soton.ac.uk/id/eprint/429781
ISSN: 0174-304X
PURE UUID: 19275afc-2439-4587-9c99-15a007d4004d
ORCID for F. Kirkham: ORCID iD orcid.org/0000-0002-2443-7958

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Date deposited: 05 Apr 2019 16:30
Last modified: 13 Jun 2019 00:37

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Contributors

Author: J.Z. Hechmatt
Author: M.C. Pitt
Author: F. Kirkham ORCID iD

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