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Diffusion weighted magnetic resonance imaging of compromised tissue in stroke

Diffusion weighted magnetic resonance imaging of compromised tissue in stroke
Diffusion weighted magnetic resonance imaging of compromised tissue in stroke

Diffusion weighted imaging (DWI) and T2 weighted magnetic resonance imaging were performed on at least two occasions in 28 children presenting with stroke. In previous reports of DWI in human stroke, eventual infarction was observed (with only one exception) in all regions in which early DWI hyperintensity occurred. In the present report, two children had regions of DWI hyperintensity which did not progress to infarction. One patient who presented with right hemiplegia showed extensive high signal on DWI, with T2 evidence of tissue swelling but without hyperintensity. DWI changes persisted over weeks, with no imaging indication of infarction. This child recovered completely. A second child who had a major vessel infarct with concomitant regions of hyperintensity on T2 weighted imaging and DWI, also had DWI hyperintensity in an adjacent territory which did not develop any subsequent evidence of infarction. Thus in clinical practice DWI can demonstrate tissue which is compromised but not irreversibly so.

Diffusion weighted imaging, Ischaemia, Magnetic resonance imaging, Stroke
0003-9888
38-41
Connelly, A.
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Chong, W.K.
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Johnson, C.L.
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Ganesan, V.
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Gadian, D.G.
2b0e526e-9bd0-4173-b5cd-ee32c8f66c57
Kirkham, F.J.
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58
Connelly, A.
0cb19e67-b09d-458b-8c30-1e9f8a279887
Chong, W.K.
bb7bc2ce-1866-4fb0-8b82-5a6d2381b67a
Johnson, C.L.
8f38166d-e2d5-450c-adb5-818ed2743c60
Ganesan, V.
0541b25d-409b-434a-b628-8df993f1d8c8
Gadian, D.G.
2b0e526e-9bd0-4173-b5cd-ee32c8f66c57
Kirkham, F.J.
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58

Connelly, A., Chong, W.K., Johnson, C.L., Ganesan, V., Gadian, D.G. and Kirkham, F.J. (1997) Diffusion weighted magnetic resonance imaging of compromised tissue in stroke. Archives of Disease in Childhood, 77 (1), 38-41. (doi:10.1136/adc.77.1.38).

Record type: Article

Abstract

Diffusion weighted imaging (DWI) and T2 weighted magnetic resonance imaging were performed on at least two occasions in 28 children presenting with stroke. In previous reports of DWI in human stroke, eventual infarction was observed (with only one exception) in all regions in which early DWI hyperintensity occurred. In the present report, two children had regions of DWI hyperintensity which did not progress to infarction. One patient who presented with right hemiplegia showed extensive high signal on DWI, with T2 evidence of tissue swelling but without hyperintensity. DWI changes persisted over weeks, with no imaging indication of infarction. This child recovered completely. A second child who had a major vessel infarct with concomitant regions of hyperintensity on T2 weighted imaging and DWI, also had DWI hyperintensity in an adjacent territory which did not develop any subsequent evidence of infarction. Thus in clinical practice DWI can demonstrate tissue which is compromised but not irreversibly so.

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More information

Published date: July 1997
Keywords: Diffusion weighted imaging, Ischaemia, Magnetic resonance imaging, Stroke

Identifiers

Local EPrints ID: 429795
URI: http://eprints.soton.ac.uk/id/eprint/429795
ISSN: 0003-9888
PURE UUID: 39a96e58-e00d-4bca-b440-22813c3fd956
ORCID for F.J. Kirkham: ORCID iD orcid.org/0000-0002-2443-7958

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Date deposited: 05 Apr 2019 16:30
Last modified: 16 Mar 2024 03:22

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Contributors

Author: A. Connelly
Author: W.K. Chong
Author: C.L. Johnson
Author: V. Ganesan
Author: D.G. Gadian
Author: F.J. Kirkham ORCID iD

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