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Diffusion and perfusion magnetic resonance imaging in childhood stroke

Diffusion and perfusion magnetic resonance imaging in childhood stroke
Diffusion and perfusion magnetic resonance imaging in childhood stroke

Two magnetic resonance imaging techniques, diffusion and perfusion imaging, are being used increasingly for evaluation of pathophysiology of stroke. This article introduces these techniques and reports some initial studies using these approaches, together with conventional T2-weighted magnetic resonance imaging, for investigation of childhood stroke. It is shown that the combination of T2-weighted and diffusion images can provide information about the timing of stroke events in childhood, and perfusion imaging can detect abnormalities not visible by other magnetic resonance imaging techniques. These magnetic resonance methods therefore should play an important role in investigation of children with stroke and could be of particular value in studies of at-risk populations of children such as those with sickle cell disease.

0883-0738
279-283
Gadian, David G.
2b0e526e-9bd0-4173-b5cd-ee32c8f66c57
Calamante, Fernando
63d493e7-04b6-4147-8353-5f487b994cab
Kirkham, Fenella J.
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58
Bynevelt, Michael
b193cce3-8cf6-4b82-ab0a-6bb739b6fa29
Johnson, Cheryl L.
bd8cd7c0-09bf-482a-ab74-8617923397d3
Porter, David A.
a918d62f-147a-40cb-9702-6d169197a5ae
Chong, Wui K.
bb7bc2ce-1866-4fb0-8b82-5a6d2381b67a
Prengler, Mara
6f2b4ccb-c630-406e-9df2-55147ccc7f5a
Connelly, Alan
b2e15ed0-c70b-4de6-ab5a-4ff6861859de
Gadian, David G.
2b0e526e-9bd0-4173-b5cd-ee32c8f66c57
Calamante, Fernando
63d493e7-04b6-4147-8353-5f487b994cab
Kirkham, Fenella J.
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58
Bynevelt, Michael
b193cce3-8cf6-4b82-ab0a-6bb739b6fa29
Johnson, Cheryl L.
bd8cd7c0-09bf-482a-ab74-8617923397d3
Porter, David A.
a918d62f-147a-40cb-9702-6d169197a5ae
Chong, Wui K.
bb7bc2ce-1866-4fb0-8b82-5a6d2381b67a
Prengler, Mara
6f2b4ccb-c630-406e-9df2-55147ccc7f5a
Connelly, Alan
b2e15ed0-c70b-4de6-ab5a-4ff6861859de

Gadian, David G., Calamante, Fernando, Kirkham, Fenella J., Bynevelt, Michael, Johnson, Cheryl L., Porter, David A., Chong, Wui K., Prengler, Mara and Connelly, Alan (2000) Diffusion and perfusion magnetic resonance imaging in childhood stroke. Journal of Child Neurology, 15 (5), 279-283. (doi:10.1177/088307380001500502).

Record type: Article

Abstract

Two magnetic resonance imaging techniques, diffusion and perfusion imaging, are being used increasingly for evaluation of pathophysiology of stroke. This article introduces these techniques and reports some initial studies using these approaches, together with conventional T2-weighted magnetic resonance imaging, for investigation of childhood stroke. It is shown that the combination of T2-weighted and diffusion images can provide information about the timing of stroke events in childhood, and perfusion imaging can detect abnormalities not visible by other magnetic resonance imaging techniques. These magnetic resonance methods therefore should play an important role in investigation of children with stroke and could be of particular value in studies of at-risk populations of children such as those with sickle cell disease.

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Published date: 1 May 2000

Identifiers

Local EPrints ID: 429819
URI: http://eprints.soton.ac.uk/id/eprint/429819
ISSN: 0883-0738
PURE UUID: 3e594d3a-1610-45c9-980e-fd3fa69869ff
ORCID for Fenella J. Kirkham: ORCID iD orcid.org/0000-0002-2443-7958

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Date deposited: 05 Apr 2019 16:30
Last modified: 03 Dec 2019 01:52

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Contributors

Author: David G. Gadian
Author: Fernando Calamante
Author: Fenella J. Kirkham ORCID iD
Author: Michael Bynevelt
Author: Cheryl L. Johnson
Author: David A. Porter
Author: Wui K. Chong
Author: Mara Prengler
Author: Alan Connelly

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