PTSA-catalyzed reaction of alkyl/aryl methyl ketones with aliphatic alcohols in the presence of selenium dioxide: A protocol for the generation of an α-ketoacetals library
PTSA-catalyzed reaction of alkyl/aryl methyl ketones with aliphatic alcohols in the presence of selenium dioxide: A protocol for the generation of an α-ketoacetals library
A novel approach has been developed for the synthesis of a wide range of α-ketoacetals by the reaction of alkyl/aryl methyl ketones and aliphatic alcohols in the presence of selenium dioxide catalyzed by p-toluenesufonic acid. This method represents a general route to obtain a wide variety of α-ketoacetals in a simple, rapid, and practical manner. This approach is particularly attractive because of the easy availability of the starting materials, mild reaction temperature, and good yields of the products. The resulting α-ketoacetals are of much synthetic value as organic intermediates.
6035-6043
Shangpliang, O. Risuklang
ba789bbc-478e-4de9-8907-55afa2fc69c0
Wanniang, Kmendashisha
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Kshiar, Baskhemlang
679a421a-8caa-4d74-876f-904f5b21d3da
Marpna, Ibakyntiew D.
e5ddb214-44ed-49c4-bb9a-caf18db93828
Lipon, Tyrchain Mitre
3edb6405-cf8d-4cee-b526-fc825286fa88
Mizar, Pushpak
631b688c-b7fb-41d7-8038-9fb48ef935c7
Myrboh, Bekington
678f513f-9816-45a4-a7e6-0783abe9671f
31 March 2019
Shangpliang, O. Risuklang
ba789bbc-478e-4de9-8907-55afa2fc69c0
Wanniang, Kmendashisha
3ef6fc22-29f4-4af1-bad6-99a68422875b
Kshiar, Baskhemlang
679a421a-8caa-4d74-876f-904f5b21d3da
Marpna, Ibakyntiew D.
e5ddb214-44ed-49c4-bb9a-caf18db93828
Lipon, Tyrchain Mitre
3edb6405-cf8d-4cee-b526-fc825286fa88
Mizar, Pushpak
631b688c-b7fb-41d7-8038-9fb48ef935c7
Myrboh, Bekington
678f513f-9816-45a4-a7e6-0783abe9671f
Shangpliang, O. Risuklang, Wanniang, Kmendashisha, Kshiar, Baskhemlang, Marpna, Ibakyntiew D., Lipon, Tyrchain Mitre, Mizar, Pushpak and Myrboh, Bekington
(2019)
PTSA-catalyzed reaction of alkyl/aryl methyl ketones with aliphatic alcohols in the presence of selenium dioxide: A protocol for the generation of an α-ketoacetals library.
ACS Omega, 4 (3), .
(doi:10.1021/acsomega.9b00361).
Abstract
A novel approach has been developed for the synthesis of a wide range of α-ketoacetals by the reaction of alkyl/aryl methyl ketones and aliphatic alcohols in the presence of selenium dioxide catalyzed by p-toluenesufonic acid. This method represents a general route to obtain a wide variety of α-ketoacetals in a simple, rapid, and practical manner. This approach is particularly attractive because of the easy availability of the starting materials, mild reaction temperature, and good yields of the products. The resulting α-ketoacetals are of much synthetic value as organic intermediates.
Text
acsomega.9b00361
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Accepted/In Press date: 26 February 2019
e-pub ahead of print date: 29 March 2019
Published date: 31 March 2019
Identifiers
Local EPrints ID: 430076
URI: http://eprints.soton.ac.uk/id/eprint/430076
ISSN: 2470-1343
PURE UUID: bfcf4bfc-80b5-4e06-8265-65e72c8633b6
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Date deposited: 11 Apr 2019 16:30
Last modified: 17 Mar 2024 12:24
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Contributors
Author:
O. Risuklang Shangpliang
Author:
Kmendashisha Wanniang
Author:
Baskhemlang Kshiar
Author:
Ibakyntiew D. Marpna
Author:
Tyrchain Mitre Lipon
Author:
Pushpak Mizar
Author:
Bekington Myrboh
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