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Numerical comparison of X-ray differential phase contrast and attenuation contrast

Numerical comparison of X-ray differential phase contrast and attenuation contrast
Numerical comparison of X-ray differential phase contrast and attenuation contrast
We present a numerical tool to compare directly the contrast-to-noise-ratio (CNR) of the attenuation- and differential phase-contrast signals available from grating-based X-ray imaging for single radiographs. The attenuation projection is differentiated to bring it into a modality comparable to the differential phase projection using a Gaussian derivative filter. A Relative Contrast Gain (RCG) is then defined as the ratio of the CNR of image values in a region of interest (ROI) in the differential phase projection to the CNR of image values in the same ROI in the differential attenuation projection. We apply the method on experimental data of human breast tissue acquired using a grating interferometer to compare the two contrast modes for two regions of interest differing in the type of tissue. Our results indicate that the proposed method can be used as a local estimate of the spatial distribution of the ratio δ/β, i.e., real and imaginary part of the complex refractive index, across a sample.
2156-7085
1141-1148
Hahn, Dieter
8d39b5e1-8745-4bfe-9919-529fc6017f8a
Thibault, Pierre
975a4c7b-6ca9-4958-b362-9eba10ab926b
Bech, Martin
e6121351-e435-49f5-83ca-b05eabad77d1
Stockmar, Marco
e01c79de-cd16-4c0c-9227-a49bd18a5138
Schleede, Simone
e9946232-668f-4211-a0f2-80f3d0ce9aef
Zanette, Irene
39ee899c-0aae-4fac-aec6-826f848a8022
Rack, Alexander
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Weitkamp, Timm
b9a2c880-940e-4149-8c1a-0c52e7dbd561
Sztrokay, Aniko
b80066fd-7a73-4df4-9f62-36fcc8309563
Schlossbauer, Thomas
9369850e-8c64-4190-8601-8da391a8526a
Bamberg, Fabian
1c0f7447-b477-42e1-a2f2-2939a714d578
Reiser, Maximilian
3c1a53fc-65c2-40b1-bcd2-30ed3d646c4a
Pfeiffer, Franz
90bfb684-c442-458c-8f10-64d0e89cbef1
Hahn, Dieter
8d39b5e1-8745-4bfe-9919-529fc6017f8a
Thibault, Pierre
975a4c7b-6ca9-4958-b362-9eba10ab926b
Bech, Martin
e6121351-e435-49f5-83ca-b05eabad77d1
Stockmar, Marco
e01c79de-cd16-4c0c-9227-a49bd18a5138
Schleede, Simone
e9946232-668f-4211-a0f2-80f3d0ce9aef
Zanette, Irene
39ee899c-0aae-4fac-aec6-826f848a8022
Rack, Alexander
5c2ef8cf-2107-49c4-ae3c-f0e29d17170b
Weitkamp, Timm
b9a2c880-940e-4149-8c1a-0c52e7dbd561
Sztrokay, Aniko
b80066fd-7a73-4df4-9f62-36fcc8309563
Schlossbauer, Thomas
9369850e-8c64-4190-8601-8da391a8526a
Bamberg, Fabian
1c0f7447-b477-42e1-a2f2-2939a714d578
Reiser, Maximilian
3c1a53fc-65c2-40b1-bcd2-30ed3d646c4a
Pfeiffer, Franz
90bfb684-c442-458c-8f10-64d0e89cbef1

Hahn, Dieter, Thibault, Pierre, Bech, Martin, Stockmar, Marco, Schleede, Simone, Zanette, Irene, Rack, Alexander, Weitkamp, Timm, Sztrokay, Aniko, Schlossbauer, Thomas, Bamberg, Fabian, Reiser, Maximilian and Pfeiffer, Franz (2012) Numerical comparison of X-ray differential phase contrast and attenuation contrast. Biomedical Optics Express, 3 (6), 1141-1148. (doi:10.1364/BOE.3.001141).

Record type: Article

Abstract

We present a numerical tool to compare directly the contrast-to-noise-ratio (CNR) of the attenuation- and differential phase-contrast signals available from grating-based X-ray imaging for single radiographs. The attenuation projection is differentiated to bring it into a modality comparable to the differential phase projection using a Gaussian derivative filter. A Relative Contrast Gain (RCG) is then defined as the ratio of the CNR of image values in a region of interest (ROI) in the differential phase projection to the CNR of image values in the same ROI in the differential attenuation projection. We apply the method on experimental data of human breast tissue acquired using a grating interferometer to compare the two contrast modes for two regions of interest differing in the type of tissue. Our results indicate that the proposed method can be used as a local estimate of the spatial distribution of the ratio δ/β, i.e., real and imaginary part of the complex refractive index, across a sample.

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More information

Accepted/In Press date: 14 March 2012
e-pub ahead of print date: 27 April 2012
Published date: 1 June 2012

Identifiers

Local EPrints ID: 430993
URI: http://eprints.soton.ac.uk/id/eprint/430993
ISSN: 2156-7085
PURE UUID: 54da3649-90c3-4dfc-a1f5-92782e4a4859
ORCID for Pierre Thibault: ORCID iD orcid.org/0000-0003-1278-8846

Catalogue record

Date deposited: 21 May 2019 16:30
Last modified: 10 Nov 2021 03:40

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Contributors

Author: Dieter Hahn
Author: Pierre Thibault ORCID iD
Author: Martin Bech
Author: Marco Stockmar
Author: Simone Schleede
Author: Irene Zanette
Author: Alexander Rack
Author: Timm Weitkamp
Author: Aniko Sztrokay
Author: Thomas Schlossbauer
Author: Fabian Bamberg
Author: Maximilian Reiser
Author: Franz Pfeiffer

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