Chip-based resonance Raman spectroscopy using tantalum pentoxide waveguides

Abstract

Blood analysis is an important diagnostic tool, as it provides a wealth of information about the patient’s health. Raman spectroscopy is a promising tool in blood analysis, but widespread clinical application is limited by its low signal strength, as well as complex and costly instrumentation. The growing field of waveguide-based Raman spectroscopy tries to solve these challenges by working towards fully integrated Raman sensors with increased interaction areas. In this work, we demonstrate resonance Raman measurements of hemoglobin, a crucial component of blood, at 532 nm excitation using a tantalum pentoxide (Ta₂O₅) waveguide platform. We have also characterized the background signal from Ta₂O₅ waveguide material when excited at 532 nm. In addition, we demonstrate spontaneous Raman measurements of iso-propanol and methanol using the same platform. Our results suggest that Ta₂O₅ is a promising waveguide platform for resonance Raman spectroscopy at 532 nm, and in particular for blood analysis.

More information

Identifiers

ORCID for Ganapathy Senthil Murugan: orcid.org/0000-0002-2733-3273

Catalogue record

Export record

Altmetrics