The University of Southampton
University of Southampton Institutional Repository

Additive inhibitory effects of combinations of fluoride and chlorhexidine on acid production by Streptococcus mutans and Streptococcus sanguis

Additive inhibitory effects of combinations of fluoride and chlorhexidine on acid production by Streptococcus mutans and Streptococcus sanguis
Additive inhibitory effects of combinations of fluoride and chlorhexidine on acid production by Streptococcus mutans and Streptococcus sanguis

The effect of 0.07 or 0.15 mMchlorhexidine (CHX) and 4.0 or 8.0 mM potassium fluoride (F), added singly and in combinations, on acid production by Streptococcus mutans and Streptococcus sanguis was studied. Cells were grown in a chemostat under different environmental conditions and acid production from glucose or sucrose was measured as a rate at pH 7.0 and by pH-fall experiments. CHX had a greater inhibitory action on S. mutans while S. sanguis was more sensitive to F. Growth conditions affected the sensitivity of both strains to the two inhibitors and, in general, cells grown glucose-limited were the most sensitive. Combinations of F and CHX showed additive inhibitory effects on acid production, irrespective of the method of measurement.

Acid production, bacterial, Chlorhexidine, Fluoride, Streptococcus mutans, Streptococcus sanguis
0008-6568
64-71
McDermid, Ann S.
34686047-11ba-41da-884d-1dc41fa7024b
Marsh, P. D.
9d226405-bfd2-432b-ac22-ea619f706805
Keevil, C. W.
cb7de0a7-ce33-4cfa-af52-07f99e5650eb
Ellwood, D. C.
a7dc8f2a-f392-42b4-a022-fa5a58cf6be6
McDermid, Ann S.
34686047-11ba-41da-884d-1dc41fa7024b
Marsh, P. D.
9d226405-bfd2-432b-ac22-ea619f706805
Keevil, C. W.
cb7de0a7-ce33-4cfa-af52-07f99e5650eb
Ellwood, D. C.
a7dc8f2a-f392-42b4-a022-fa5a58cf6be6

McDermid, Ann S., Marsh, P. D., Keevil, C. W. and Ellwood, D. C. (1985) Additive inhibitory effects of combinations of fluoride and chlorhexidine on acid production by Streptococcus mutans and Streptococcus sanguis. Caries Research, 19 (1), 64-71. (doi:10.1159/000260830).

Record type: Article

Abstract

The effect of 0.07 or 0.15 mMchlorhexidine (CHX) and 4.0 or 8.0 mM potassium fluoride (F), added singly and in combinations, on acid production by Streptococcus mutans and Streptococcus sanguis was studied. Cells were grown in a chemostat under different environmental conditions and acid production from glucose or sucrose was measured as a rate at pH 7.0 and by pH-fall experiments. CHX had a greater inhibitory action on S. mutans while S. sanguis was more sensitive to F. Growth conditions affected the sensitivity of both strains to the two inhibitors and, in general, cells grown glucose-limited were the most sensitive. Combinations of F and CHX showed additive inhibitory effects on acid production, irrespective of the method of measurement.

Full text not available from this repository.

More information

Published date: 1985
Keywords: Acid production, bacterial, Chlorhexidine, Fluoride, Streptococcus mutans, Streptococcus sanguis

Identifiers

Local EPrints ID: 431316
URI: http://eprints.soton.ac.uk/id/eprint/431316
ISSN: 0008-6568
PURE UUID: b5e9adee-a4d8-4f03-8006-294d457091de
ORCID for C. W. Keevil: ORCID iD orcid.org/0000-0003-1917-7706

Catalogue record

Date deposited: 29 May 2019 16:30
Last modified: 30 May 2019 00:36

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×