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Growth temperature reversibly modulates the virulence of Legionella pneumophila

Growth temperature reversibly modulates the virulence of Legionella pneumophila
Growth temperature reversibly modulates the virulence of Legionella pneumophila

In chemostat culture, the virulence of two strains of Legionella pneumophila was shown to be significantly (P < 0.05) reduced when the culture temperature was lowered from 37 to 24°C. This modulation was reversed by returning the temperature to 37°C, which resulted in a statistically significant (P < 0.05) increase in virulence.

0019-9567
2995-2997
Mauchline, W. S.
80ed42b2-235d-4e4b-998b-bb928a52daa2
James, B. W.
2982ef34-33f6-4dd1-bc54-03b0333f3339
Fitzgeorge, R. B.
af44691f-36fb-44fc-b2ac-f5125080667c
Dennis, P. J.
25bd2523-2802-498f-9a17-80ecea7db112
Keevil, C. W.
cb7de0a7-ce33-4cfa-af52-07f99e5650eb
Mauchline, W. S.
80ed42b2-235d-4e4b-998b-bb928a52daa2
James, B. W.
2982ef34-33f6-4dd1-bc54-03b0333f3339
Fitzgeorge, R. B.
af44691f-36fb-44fc-b2ac-f5125080667c
Dennis, P. J.
25bd2523-2802-498f-9a17-80ecea7db112
Keevil, C. W.
cb7de0a7-ce33-4cfa-af52-07f99e5650eb

Mauchline, W. S., James, B. W., Fitzgeorge, R. B., Dennis, P. J. and Keevil, C. W. (1994) Growth temperature reversibly modulates the virulence of Legionella pneumophila. Infection and Immunity, 62 (7), 2995-2997.

Record type: Letter

Abstract

In chemostat culture, the virulence of two strains of Legionella pneumophila was shown to be significantly (P < 0.05) reduced when the culture temperature was lowered from 37 to 24°C. This modulation was reversed by returning the temperature to 37°C, which resulted in a statistically significant (P < 0.05) increase in virulence.

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Published date: 1 July 1994
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Identifiers

Local EPrints ID: 431338
URI: http://eprints.soton.ac.uk/id/eprint/431338
ISSN: 0019-9567
PURE UUID: 3544ee3c-bc0c-4695-aac9-972b061a947f
ORCID for C. W. Keevil: ORCID iD orcid.org/0000-0003-1917-7706

Catalogue record

Date deposited: 29 May 2019 16:30
Last modified: 16 Mar 2024 03:24

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Contributors

Author: W. S. Mauchline
Author: B. W. James
Author: R. B. Fitzgeorge
Author: P. J. Dennis
Author: C. W. Keevil ORCID iD

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