Developing differences: early-life effects and evolutionary medicine
Developing differences: early-life effects and evolutionary medicine
Variation in early-life conditions can trigger developmental switches that lead to predictable individual differences in adult behaviour and physiology. Despite evidence for such early-life effects being widespread both in humans and throughout the animal kingdom, the evolutionary causes and consequences of this developmental plasticity remain unclear. The current issue aims to bring together studies of early-life effects from the fields of both evolutionary ecology and biomedicine to synthesise and advance current knowledge of how information is used during development, the mechanisms involved, and how early-life effects evolved. We hope this will stimulate further research into early-life effects, improving our understanding of why individuals differ and how this might influence their susceptibility to disease. This article is part of the theme issue ‘Developing differences: early-life effects and evolutionary medicine’.
Developmental plasticity, Epigenetics, Growth, Nutrition, Parental effect, Predictive adaptive response
1-7
Kuijper, Bram
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Hanson, Mark A.
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Vitikainen, Emma I.K.
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Marshall, Harry H.
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Ozanne, Susan E.
bba0ebbc-1d8d-497c-ad46-518ca6e52f3a
Cant, Michael A.
ce472b47-7490-4fe5-b104-64f864755ffc
April 2019
Kuijper, Bram
f4f90923-ed35-4fba-82fb-8f396d83f1cc
Hanson, Mark A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Vitikainen, Emma I.K.
f05e18f3-9a6d-408c-9cde-591794df685e
Marshall, Harry H.
74b2deff-d6c4-41ee-932a-de957543b431
Ozanne, Susan E.
bba0ebbc-1d8d-497c-ad46-518ca6e52f3a
Cant, Michael A.
ce472b47-7490-4fe5-b104-64f864755ffc
Kuijper, Bram, Hanson, Mark A., Vitikainen, Emma I.K., Marshall, Harry H., Ozanne, Susan E. and Cant, Michael A.
(2019)
Developing differences: early-life effects and evolutionary medicine.
Philosophical Transactions of the Royal Society B: Biological Sciences, 374 (1770), , [20190039].
(doi:10.1098/rstb.2019.0039).
Abstract
Variation in early-life conditions can trigger developmental switches that lead to predictable individual differences in adult behaviour and physiology. Despite evidence for such early-life effects being widespread both in humans and throughout the animal kingdom, the evolutionary causes and consequences of this developmental plasticity remain unclear. The current issue aims to bring together studies of early-life effects from the fields of both evolutionary ecology and biomedicine to synthesise and advance current knowledge of how information is used during development, the mechanisms involved, and how early-life effects evolved. We hope this will stimulate further research into early-life effects, improving our understanding of why individuals differ and how this might influence their susceptibility to disease. This article is part of the theme issue ‘Developing differences: early-life effects and evolutionary medicine’.
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More information
Accepted/In Press date: 29 January 2019
e-pub ahead of print date: 25 February 2019
Published date: April 2019
Keywords:
Developmental plasticity, Epigenetics, Growth, Nutrition, Parental effect, Predictive adaptive response
Identifiers
Local EPrints ID: 431413
URI: http://eprints.soton.ac.uk/id/eprint/431413
ISSN: 0962-8436
PURE UUID: 1df85c3f-b21c-4916-961a-1d63b38214d6
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Date deposited: 31 May 2019 16:30
Last modified: 06 Jun 2024 01:39
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Contributors
Author:
Bram Kuijper
Author:
Emma I.K. Vitikainen
Author:
Harry H. Marshall
Author:
Susan E. Ozanne
Author:
Michael A. Cant
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