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Nephrolithiasis in the obese patient

Nephrolithiasis in the obese patient
Nephrolithiasis in the obese patient

Purpose of Review: the link between metabolic syndrome (MetS)/obesity and kidney stone disease (KSD) has gained importance over recent years due to the increasing prevalence and healthcare burden worldwide. This review analyses the literature exploring the link between MetS/obesity and KSD and the impact that obesity has on KSD management. 

Recent Findings: metabolic syndrome has been shown to increase an individual’s risk of developing kidney stone disease, with insulin resistance forming a core component of the pathophysiology. The body habitus of an individual also influences the type of intervention that is most appropriate, with flexible ureteroscopy increasingly being the preferred option in obese patients. 

Summary: it is important for urologists to consider the features of metabolic syndrome to effectively manage episodes of KSD in obese patients. In addition, better quality evidence is required to effectively compare different treatment options in this group of patients.

Flexible ureteroscopy, Insulin resistance, Kidney stone disease, Metabolic syndrome, Obese, Percutaneous nephrolithotomy, RIRS, Shock wave lithotripsy, URS
1527-2737
Kelly, Claire
4d078e8e-71eb-4f1a-bb57-cdf95aa81f32
Geraghty, Robert M.
65977705-49f3-48b7-8a80-a86c26955755
Somani, Bhaskar K.
ab5fd1ce-02df-4b88-b25e-8ece396335d9
Kelly, Claire
4d078e8e-71eb-4f1a-bb57-cdf95aa81f32
Geraghty, Robert M.
65977705-49f3-48b7-8a80-a86c26955755
Somani, Bhaskar K.
ab5fd1ce-02df-4b88-b25e-8ece396335d9

Kelly, Claire, Geraghty, Robert M. and Somani, Bhaskar K. (2019) Nephrolithiasis in the obese patient. Current Urology Reports, 20 (7), [36]. (doi:10.1007/s11934-019-0898-0).

Record type: Review

Abstract

Purpose of Review: the link between metabolic syndrome (MetS)/obesity and kidney stone disease (KSD) has gained importance over recent years due to the increasing prevalence and healthcare burden worldwide. This review analyses the literature exploring the link between MetS/obesity and KSD and the impact that obesity has on KSD management. 

Recent Findings: metabolic syndrome has been shown to increase an individual’s risk of developing kidney stone disease, with insulin resistance forming a core component of the pathophysiology. The body habitus of an individual also influences the type of intervention that is most appropriate, with flexible ureteroscopy increasingly being the preferred option in obese patients. 

Summary: it is important for urologists to consider the features of metabolic syndrome to effectively manage episodes of KSD in obese patients. In addition, better quality evidence is required to effectively compare different treatment options in this group of patients.

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e-pub ahead of print date: 18 May 2019
Published date: July 2019
Keywords: Flexible ureteroscopy, Insulin resistance, Kidney stone disease, Metabolic syndrome, Obese, Percutaneous nephrolithotomy, RIRS, Shock wave lithotripsy, URS

Identifiers

Local EPrints ID: 431736
URI: http://eprints.soton.ac.uk/id/eprint/431736
ISSN: 1527-2737
PURE UUID: b7f0bf62-72ac-4442-9127-7285c9ba7b66

Catalogue record

Date deposited: 14 Jun 2019 16:30
Last modified: 16 Mar 2024 02:15

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Contributors

Author: Claire Kelly
Author: Robert M. Geraghty

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