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A comparison of three outcome measures of the impact of vasomotor symptoms on women’s lives

A comparison of three outcome measures of the impact of vasomotor symptoms on women’s lives
A comparison of three outcome measures of the impact of vasomotor symptoms on women’s lives

Objective: Measures of the impact of vasomotor symptoms (VMS) have been used as outcomes in clinical trials but have not been compared. This study compares the Hot Flush Rating Scale (HFRS), the Hot Flash Related Daily Interference Scale (HFRDIS), and the shorter Hot Flash Interference (HFI) scale.

Methods: Baseline data were taken from two studies including healthy women (menopause transition or postmenopause) and breast cancer patients experiencing VMS. Participants completed questionnaires on sociodemographics, the HFRS, the HFRDIS, the HFI, the Work and Social Adjustment Scale (WSAS), on depression (Generalized Anxiety Disorder 7), on anxiety (Patient Health Questionnaire 9), and on use of medical services.

Results: A total of 169 women (129 with history of breast cancer and 40 without) aged 54.47 (standard deviation [SD] = 9.11) years took part. They had an average of 66 (SD = 40.94) VMS per week, with a mean HFRS problem-rating of 6.53 (SD = 1.99), HFRDIS score of 5.36 (SD = 2.22), and HFI score of 6.13 (SD = 2.30). The HFRS problem-rating, HFRDIS, and HFI were significantly associated (r = 0.61–0.85), had good internal reliability (α = 0.76–0.91), and had significant concurrent validity with mood, the WSAS, and use of medical services. VMS frequency was not associated with mood, the WSAS, or use of medical services.

Conclusion: The HFRS problem-rating scale and the HFI are two brief, three-item measures that measure a similar concept of VMS interference/impact, with evidence of reliability and validity.

Flushes, hot flashes, interference, measures, vasomotor symptoms
1369-7137
419-423
Hunter, M.S.
fce15222-f73f-478a-87fd-d480cac6fd2a
Nuttall, J.
154aec0a-05f2-4379-918e-9c36767fdc4c
Fenlon, D.
52f9a9f1-1643-449c-9856-258ef563342c
Hunter, M.S.
fce15222-f73f-478a-87fd-d480cac6fd2a
Nuttall, J.
154aec0a-05f2-4379-918e-9c36767fdc4c
Fenlon, D.
52f9a9f1-1643-449c-9856-258ef563342c

Hunter, M.S., Nuttall, J. and Fenlon, D. (2019) A comparison of three outcome measures of the impact of vasomotor symptoms on women’s lives. Climacteric, 22 (4), 419-423. (doi:10.1080/13697137.2019.1580258).

Record type: Article

Abstract

Objective: Measures of the impact of vasomotor symptoms (VMS) have been used as outcomes in clinical trials but have not been compared. This study compares the Hot Flush Rating Scale (HFRS), the Hot Flash Related Daily Interference Scale (HFRDIS), and the shorter Hot Flash Interference (HFI) scale.

Methods: Baseline data were taken from two studies including healthy women (menopause transition or postmenopause) and breast cancer patients experiencing VMS. Participants completed questionnaires on sociodemographics, the HFRS, the HFRDIS, the HFI, the Work and Social Adjustment Scale (WSAS), on depression (Generalized Anxiety Disorder 7), on anxiety (Patient Health Questionnaire 9), and on use of medical services.

Results: A total of 169 women (129 with history of breast cancer and 40 without) aged 54.47 (standard deviation [SD] = 9.11) years took part. They had an average of 66 (SD = 40.94) VMS per week, with a mean HFRS problem-rating of 6.53 (SD = 1.99), HFRDIS score of 5.36 (SD = 2.22), and HFI score of 6.13 (SD = 2.30). The HFRS problem-rating, HFRDIS, and HFI were significantly associated (r = 0.61–0.85), had good internal reliability (α = 0.76–0.91), and had significant concurrent validity with mood, the WSAS, and use of medical services. VMS frequency was not associated with mood, the WSAS, or use of medical services.

Conclusion: The HFRS problem-rating scale and the HFI are two brief, three-item measures that measure a similar concept of VMS interference/impact, with evidence of reliability and validity.

Full text not available from this repository.

More information

Accepted/In Press date: 3 February 2019
e-pub ahead of print date: 25 March 2019
Keywords: Flushes, hot flashes, interference, measures, vasomotor symptoms

Identifiers

Local EPrints ID: 432593
URI: http://eprints.soton.ac.uk/id/eprint/432593
ISSN: 1369-7137
PURE UUID: 3df54fee-6f5e-4775-b93e-9e6e4d0baab5

Catalogue record

Date deposited: 19 Jul 2019 16:36
Last modified: 06 Oct 2020 18:30

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