Laser direct-write patterned paper-based devices for detection of bacterial pathogens
Laser direct-write patterned paper-based devices for detection of bacterial pathogens
World Health Organization has identified antimicrobial resistance as one of the most serious global threat that require urgent actions. Therefore, we report on the fabrication of novel paper-based culture devices that allow prompt detection of bacterial pathogens and their antimicrobial resistance at the point-of-care. These unique devices were fabricated using a laser direct-write technique that relies on light-induced polymerization. Multiple well-like structures, laser-patterned in the paper-devices, and impregnated with agar (containing different antibiotics in various doses) allowed the selective growth/inhibition and thus detection/susceptibility-testing of E.coli/Pa (primary causes of urinary and upper respiratory tract infections) via a simple visually observable colour-change.
He, Peijun
2e303166-6aa5-4a09-b22e-440d96a54a9f
Katis, Ioannis
f92dfb8f-610d-4877-83f6-fd26a571df12
Bryant, Catherine
d53ab6c9-909d-43cb-84fc-3e197df377f3
Keevil, Charles
cb7de0a7-ce33-4cfa-af52-07f99e5650eb
Somani, Bhaskar
ab5fd1ce-02df-4b88-b25e-8ece396335d9
Eason, Robert
e38684c3-d18c-41b9-a4aa-def67283b020
Sones, Collin
9de9d8ee-d394-46a5-80b7-e341c0eed0a8
February 2019
He, Peijun
2e303166-6aa5-4a09-b22e-440d96a54a9f
Katis, Ioannis
f92dfb8f-610d-4877-83f6-fd26a571df12
Bryant, Catherine
d53ab6c9-909d-43cb-84fc-3e197df377f3
Keevil, Charles
cb7de0a7-ce33-4cfa-af52-07f99e5650eb
Somani, Bhaskar
ab5fd1ce-02df-4b88-b25e-8ece396335d9
Eason, Robert
e38684c3-d18c-41b9-a4aa-def67283b020
Sones, Collin
9de9d8ee-d394-46a5-80b7-e341c0eed0a8
He, Peijun, Katis, Ioannis, Bryant, Catherine, Keevil, Charles, Somani, Bhaskar, Eason, Robert and Sones, Collin
(2019)
Laser direct-write patterned paper-based devices for detection of bacterial pathogens.
Gray, Bonnie L. and Becker, Holger
(eds.)
In Microfluidics, BioMEMS, and Medical Microsystems XVII.
vol. 10875,
SPIE..
(doi:10.1117/12.2506790).
Record type:
Conference or Workshop Item
(Paper)
Abstract
World Health Organization has identified antimicrobial resistance as one of the most serious global threat that require urgent actions. Therefore, we report on the fabrication of novel paper-based culture devices that allow prompt detection of bacterial pathogens and their antimicrobial resistance at the point-of-care. These unique devices were fabricated using a laser direct-write technique that relies on light-induced polymerization. Multiple well-like structures, laser-patterned in the paper-devices, and impregnated with agar (containing different antibiotics in various doses) allowed the selective growth/inhibition and thus detection/susceptibility-testing of E.coli/Pa (primary causes of urinary and upper respiratory tract infections) via a simple visually observable colour-change.
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More information
Published date: February 2019
Additional Information:
ISSN 1996-756X
Venue - Dates:
Photonics West, The Moscone Center, San Francisco, United States, 2019-02-01 - 2019-02-06
Identifiers
Local EPrints ID: 433024
URI: http://eprints.soton.ac.uk/id/eprint/433024
PURE UUID: 4085bb83-f15a-49a7-8c86-ce45feb9189d
Catalogue record
Date deposited: 06 Aug 2019 16:30
Last modified: 17 Mar 2024 02:35
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Contributors
Author:
Catherine Bryant
Editor:
Bonnie L. Gray
Editor:
Holger Becker
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