Outcomes and long-term follow-up of patients with cystine stones: a systematic review

Moore, Sacha L., Cook, Paul, de Coninck, Vincent, Keller, Etienne Xavier, Traxer, Olivier, Dragos, Laurian, Shergill, Iqbal S. and Somani, Bhaskar K. (2019) Outcomes and long-term follow-up of patients with cystine stones: a systematic review. Current Urology Reports, 20 (6), [27]. (doi:10.1007/s11934-019-0891-7).

Abstract

PURPOSE OF REVIEW: Cystine stone patients can be difficult to manage with frequent recurrences. We performed a systematic review with a view to assessing interventions, compliance and their long-term outcomes.

RECENT FINDINGS: Ten retrospective observational studies (253 patients) assessed the outcomes and long-term follow-up of cystine stone patients. The mean length of follow-up was 9.6 years (range 3.5-21.8 years). The overall mean number of surgical procedures/patient was 5.7 (range 2-9.8/patient) with the overall mean number of surgical procedures/patient/year at 0.59 (range 0.22-1.32/patient/year). While open surgery has decreased over the last decade and PCNL has been stable, there seems to be a rise of RIRS during this period. Patients with cystine stones need periodic interventions for stone recurrences despite medical management, with limited data showing the impact on renal function. While the management is individualised, wide variability exists with often poor and incomplete patient data.

This record has no associated files available for download.

Contributors

Download statistics