The University of Southampton
University of Southampton Institutional Repository

Aflibercept in the real world–are the visual outcomes worse in patients with diabetic macular edema who have had a cataract operation?

Aflibercept in the real world–are the visual outcomes worse in patients with diabetic macular edema who have had a cataract operation?
Aflibercept in the real world–are the visual outcomes worse in patients with diabetic macular edema who have had a cataract operation?
Aflibercept was licenced in UK for use as treatment for diabetic macular edema in 2015. Here we compare visual outcomes over 12 months between those who had previously had cataract surgery and those who had not.

Methods: Anonymised data of patients undergoing antiVEGF injections for diabetic macular edema were exported from a dedicated ophthalmology electronic patient record system. Those who had aflibercept injections only were included. Patients were included if lens status in each injection record in 12 months “phakic” or if each lens status was “pseudophakic”. The first eye treated in each patient was used. Wilcoxon Rank Sum test was used to compare groups. Linear regression was used to relate change in visual acuity (VA) over 12 months from the first injection lens status, age, baseline ETDRS letter score and number of injections. The 12 month letter score was that at the visit after the …
0146-0404
2637
Stratton, Irene
4959ee5f-52b7-4a14-a614-aad9278c6753
Scanlon, Peter Henry
4e3d2310-c79e-42db-ae29-7a7d6b278aa3
Talks, James S.
3c9e94ea-9991-424c-936c-3058530435f3
Chakravarthy, Usha
2c06cdaf-94c0-409a-8eff-2f624c120a5e
Mukherjee, Rajarshi
32026aa1-85da-44f4-b6fb-895503691995
Ghanchi, Faruque
8dee49a5-5e08-4ed9-b28d-76439e79d602
Mahmood, Sajjad
4d683bfb-b232-4a64-91bc-9b7f6ab89d2e
Lotery, Andrew
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Stratton, Irene
4959ee5f-52b7-4a14-a614-aad9278c6753
Scanlon, Peter Henry
4e3d2310-c79e-42db-ae29-7a7d6b278aa3
Talks, James S.
3c9e94ea-9991-424c-936c-3058530435f3
Chakravarthy, Usha
2c06cdaf-94c0-409a-8eff-2f624c120a5e
Mukherjee, Rajarshi
32026aa1-85da-44f4-b6fb-895503691995
Ghanchi, Faruque
8dee49a5-5e08-4ed9-b28d-76439e79d602
Mahmood, Sajjad
4d683bfb-b232-4a64-91bc-9b7f6ab89d2e
Lotery, Andrew
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514

Stratton, Irene, Scanlon, Peter Henry, Talks, James S., Chakravarthy, Usha, Mukherjee, Rajarshi, Ghanchi, Faruque, Mahmood, Sajjad and Lotery, Andrew (2019) Aflibercept in the real world–are the visual outcomes worse in patients with diabetic macular edema who have had a cataract operation? Investigative Ophthalmology & Visual Science, 60 (9), 2637.

Record type: Meeting abstract

Abstract

Aflibercept was licenced in UK for use as treatment for diabetic macular edema in 2015. Here we compare visual outcomes over 12 months between those who had previously had cataract surgery and those who had not.

Methods: Anonymised data of patients undergoing antiVEGF injections for diabetic macular edema were exported from a dedicated ophthalmology electronic patient record system. Those who had aflibercept injections only were included. Patients were included if lens status in each injection record in 12 months “phakic” or if each lens status was “pseudophakic”. The first eye treated in each patient was used. Wilcoxon Rank Sum test was used to compare groups. Linear regression was used to relate change in visual acuity (VA) over 12 months from the first injection lens status, age, baseline ETDRS letter score and number of injections. The 12 month letter score was that at the visit after the …

This record has no associated files available for download.

More information

Published date: 22 July 2019

Identifiers

Local EPrints ID: 433971
URI: http://eprints.soton.ac.uk/id/eprint/433971
ISSN: 0146-0404
PURE UUID: 25bc7dc2-5437-4834-b529-c4ede3715a5c
ORCID for Andrew Lotery: ORCID iD orcid.org/0000-0001-5541-4305

Catalogue record

Date deposited: 09 Sep 2019 16:30
Last modified: 17 Mar 2024 02:57

Export record

Contributors

Author: Irene Stratton
Author: Peter Henry Scanlon
Author: James S. Talks
Author: Usha Chakravarthy
Author: Rajarshi Mukherjee
Author: Faruque Ghanchi
Author: Sajjad Mahmood
Author: Andrew Lotery ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×