The design and implementation of a passive cavitation detection system for use with ex vivo tissue
The design and implementation of a passive cavitation detection system for use with ex vivo tissue
A passive cavitation detection (PCD) system has been constructed around a National Physical Laboratory (NPL) cavitation sensor. This system, which has been used to detect the acoustic emissions when ex vivo tissue is exposed to a number of different HIFU intensities, can monitor acoustic emissions throughout an exposure. It has been observed that for the higher harmonics, specifically the 4th (6.77 MHz), the emissions undergo a sharp transition from a low magnitude slowly varying signal, to rapidly varying and high magnitude signal. A sonochemical reaction (in a potassium iodide solution) was simultaneously monitored with the passive cavitation detection and a correlation with free radical production (caused by inertial cavitation) and high frequency broadband emission (7–8 MHz) was observed.
cavitation, sensors, biomedical ultrasonics, biological tissues
073540321X
338-342
American Institute of Physics
McLaughlan, James
67d90c91-797a-412b-98b5-41acaeffbc52
Rivens, Ian
21ac1940-a62b-429b-886e-9412e55a7ffd
ter Haar, Gail
b7c05011-3bb9-4669-a049-4c22fc70f548
Shaw, Adam
cca8f84a-f3ea-4e47-8c16-d757e7a38e06
Leighton, Timothy
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Humphrey, Victor
23c9bd0c-7870-428f-b0dd-5ff158d22590
Birkin, Peter
ba466560-f27c-418d-89fc-67ea4f81d0a7
Vian, Chris
c5ca4c67-5a34-475e-b99b-04593f9c6cc9
2006
McLaughlan, James
67d90c91-797a-412b-98b5-41acaeffbc52
Rivens, Ian
21ac1940-a62b-429b-886e-9412e55a7ffd
ter Haar, Gail
b7c05011-3bb9-4669-a049-4c22fc70f548
Shaw, Adam
cca8f84a-f3ea-4e47-8c16-d757e7a38e06
Leighton, Timothy
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Humphrey, Victor
23c9bd0c-7870-428f-b0dd-5ff158d22590
Birkin, Peter
ba466560-f27c-418d-89fc-67ea4f81d0a7
Vian, Chris
c5ca4c67-5a34-475e-b99b-04593f9c6cc9
McLaughlan, James, Rivens, Ian, ter Haar, Gail, Shaw, Adam, Leighton, Timothy, Humphrey, Victor, Birkin, Peter and Vian, Chris
(2006)
The design and implementation of a passive cavitation detection system for use with ex vivo tissue.
In Therapeutic Ultrasound: 5th International Symposium on Therapeutic Ultrasound. AIP Conference Proceedings.
American Institute of Physics.
.
(doi:10.1063/1.2205493).
Record type:
Conference or Workshop Item
(Paper)
Abstract
A passive cavitation detection (PCD) system has been constructed around a National Physical Laboratory (NPL) cavitation sensor. This system, which has been used to detect the acoustic emissions when ex vivo tissue is exposed to a number of different HIFU intensities, can monitor acoustic emissions throughout an exposure. It has been observed that for the higher harmonics, specifically the 4th (6.77 MHz), the emissions undergo a sharp transition from a low magnitude slowly varying signal, to rapidly varying and high magnitude signal. A sonochemical reaction (in a potassium iodide solution) was simultaneously monitored with the passive cavitation detection and a correlation with free radical production (caused by inertial cavitation) and high frequency broadband emission (7–8 MHz) was observed.
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Published date: 2006
Venue - Dates:
Therapeutic Ultrasound: 5th International Symposium on Therapeutic Ultrasound, Boston, USA, 2005-10-27 - 2005-10-29
Keywords:
cavitation, sensors, biomedical ultrasonics, biological tissues
Identifiers
Local EPrints ID: 43411
URI: http://eprints.soton.ac.uk/id/eprint/43411
ISBN: 073540321X
PURE UUID: 3c736e22-a84f-4047-9cd9-a7c17ee97c20
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Date deposited: 14 Feb 2007
Last modified: 16 Mar 2024 03:34
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Contributors
Author:
James McLaughlan
Author:
Ian Rivens
Author:
Gail ter Haar
Author:
Adam Shaw
Author:
Chris Vian
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