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The design and implementation of a passive cavitation detection system for use with ex vivo tissue

The design and implementation of a passive cavitation detection system for use with ex vivo tissue
The design and implementation of a passive cavitation detection system for use with ex vivo tissue
A passive cavitation detection (PCD) system has been constructed around a National Physical Laboratory (NPL) cavitation sensor. This system, which has been used to detect the acoustic emissions when ex vivo tissue is exposed to a number of different HIFU intensities, can monitor acoustic emissions throughout an exposure. It has been observed that for the higher harmonics, specifically the 4th (6.77 MHz), the emissions undergo a sharp transition from a low magnitude slowly varying signal, to rapidly varying and high magnitude signal. A sonochemical reaction (in a potassium iodide solution) was simultaneously monitored with the passive cavitation detection and a correlation with free radical production (caused by inertial cavitation) and high frequency broadband emission (7–8 MHz) was observed.
cavitation, sensors, biomedical ultrasonics, biological tissues
073540321X
338-342
American Institute of Physics
McLaughlan, James
67d90c91-797a-412b-98b5-41acaeffbc52
Rivens, Ian
21ac1940-a62b-429b-886e-9412e55a7ffd
ter Haar, Gail
b7c05011-3bb9-4669-a049-4c22fc70f548
Shaw, Adam
cca8f84a-f3ea-4e47-8c16-d757e7a38e06
Leighton, Timothy
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Humphrey, Victor
23c9bd0c-7870-428f-b0dd-5ff158d22590
Birkin, Peter
ba466560-f27c-418d-89fc-67ea4f81d0a7
Vian, Chris
c5ca4c67-5a34-475e-b99b-04593f9c6cc9
McLaughlan, James
67d90c91-797a-412b-98b5-41acaeffbc52
Rivens, Ian
21ac1940-a62b-429b-886e-9412e55a7ffd
ter Haar, Gail
b7c05011-3bb9-4669-a049-4c22fc70f548
Shaw, Adam
cca8f84a-f3ea-4e47-8c16-d757e7a38e06
Leighton, Timothy
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Humphrey, Victor
23c9bd0c-7870-428f-b0dd-5ff158d22590
Birkin, Peter
ba466560-f27c-418d-89fc-67ea4f81d0a7
Vian, Chris
c5ca4c67-5a34-475e-b99b-04593f9c6cc9

McLaughlan, James, Rivens, Ian, ter Haar, Gail, Shaw, Adam, Leighton, Timothy, Humphrey, Victor, Birkin, Peter and Vian, Chris (2006) The design and implementation of a passive cavitation detection system for use with ex vivo tissue. In Therapeutic Ultrasound: 5th International Symposium on Therapeutic Ultrasound. AIP Conference Proceedings. American Institute of Physics. pp. 338-342 . (doi:10.1063/1.2205493).

Record type: Conference or Workshop Item (Paper)

Abstract

A passive cavitation detection (PCD) system has been constructed around a National Physical Laboratory (NPL) cavitation sensor. This system, which has been used to detect the acoustic emissions when ex vivo tissue is exposed to a number of different HIFU intensities, can monitor acoustic emissions throughout an exposure. It has been observed that for the higher harmonics, specifically the 4th (6.77 MHz), the emissions undergo a sharp transition from a low magnitude slowly varying signal, to rapidly varying and high magnitude signal. A sonochemical reaction (in a potassium iodide solution) was simultaneously monitored with the passive cavitation detection and a correlation with free radical production (caused by inertial cavitation) and high frequency broadband emission (7–8 MHz) was observed.

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More information

Published date: 2006
Venue - Dates: Therapeutic Ultrasound: 5th International Symposium on Therapeutic Ultrasound, 2005-10-27 - 2005-10-29
Keywords: cavitation, sensors, biomedical ultrasonics, biological tissues

Identifiers

Local EPrints ID: 43411
URI: https://eprints.soton.ac.uk/id/eprint/43411
ISBN: 073540321X
PURE UUID: 3c736e22-a84f-4047-9cd9-a7c17ee97c20
ORCID for Timothy Leighton: ORCID iD orcid.org/0000-0002-1649-8750
ORCID for Victor Humphrey: ORCID iD orcid.org/0000-0002-3580-5373
ORCID for Peter Birkin: ORCID iD orcid.org/0000-0002-6656-4074

Catalogue record

Date deposited: 14 Feb 2007
Last modified: 20 Jul 2019 01:21

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Contributors

Author: James McLaughlan
Author: Ian Rivens
Author: Gail ter Haar
Author: Adam Shaw
Author: Victor Humphrey ORCID iD
Author: Peter Birkin ORCID iD
Author: Chris Vian

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