The University of Southampton
University of Southampton Institutional Repository

A model of vental cochlear nucleus units based on first order intervals

Record type: Conference or Workshop Item (Paper)

Significant parallel processing occurs at the level of the ventral cochlear nucleus (VCN). It is believed that underlying this processing are discrete cellular response types which have a unique signature in their temporal adaptation patterns (TAPs). However, in reality it is difficult to define these TAPS as discrete. Here we demonstrate that a large sample (n=874) of VCN neurons can be accurately modelled as belonging to a continuous parameter space, even if they were not classifiable using traditional methods (Blackburn and Sachs, 1988). We constructed first order interspike interval distributions (FOIDs) from the responses to 50ms best-frequency tone bursts. FOIDs were then plotted on a logarithmic time axis and fitted with an “extreme value distribution” (EVD). The EVD is a variation of the statistical “central limit theorem” that states that the distribution of the extreme values of arbitrary populations has a defined EVD. EVDs predict the probability of the occurrence of rare events independently of the underlying probability function. The validity of the fit was checked by a Kolgomorov-Smirnov test. EVDs fitted more units than other models (e.g. normal, gamma, weibull, exponential). Therefore the probability for spike generation can be described statistically without knowing the exact underlying mechanism. The two parameters of the fitted FOID (mean and variance) uniformly fill a well defined area of the parameter space. Single unit types recorded from the VCN occupy different, slightly overlapping areas of this parameter space. An “automatic classification” scheme (measuring the distance to population means) closely matches the classification schemes traditionally used by physiologists.

Full text not available from this repository.

Citation

Bleeck, S. and Winter, I.M. (2006) A model of vental cochlear nucleus units based on first order intervals At BSA Short Papers Meeting on Experimental Studies of Hearing and Deafness. 14 - 15 Sep 2006.

More information

Published date: 2006
Venue - Dates: BSA Short Papers Meeting on Experimental Studies of Hearing and Deafness, 2006-09-14 - 2006-09-15
Organisations: Human Sciences Group

Identifiers

Local EPrints ID: 43461
URI: http://eprints.soton.ac.uk/id/eprint/43461
PURE UUID: f714b7da-7c57-4c1d-989f-55820422a1b7
ORCID for S. Bleeck: ORCID iD orcid.org/0000-0003-4378-3394

Catalogue record

Date deposited: 14 Feb 2007
Last modified: 17 Jul 2017 15:18

Export record

Contributors

Author: S. Bleeck ORCID iD
Author: I.M. Winter

University divisions


Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×