The University of Southampton
University of Southampton Institutional Repository

Hedgehog activation in CLL

Hedgehog activation in CLL
Hedgehog activation in CLL

In this issue of Blood, Ghia et al observe that a proportion of patients with chronic lymphocytic leukemia (CLL) harbor mutations in genes involved in the Hedgehog (Hh) pathway resulting in expression of glioma-associated oncogene homolog 1 (GLI1). They also find that GLI1 is expressed in CLL cells without evidence of Hh mutations and that the high GLI1 levels correlate with disease progression.

0006-4971
2628-2630
Chiodin, Giorgia
4b3e9525-b377-4d16-b69a-e05d2e7854fe
Forconi, Francesco
ce9ed873-58cf-4876-bf3a-9ba1d163edc8
Chiodin, Giorgia
4b3e9525-b377-4d16-b69a-e05d2e7854fe
Forconi, Francesco
ce9ed873-58cf-4876-bf3a-9ba1d163edc8

Chiodin, Giorgia and Forconi, Francesco (2019) Hedgehog activation in CLL. Blood, 133 (25), 2628-2630. (doi:10.1182/blood-2019-04-901165).

Record type: Review

Abstract

In this issue of Blood, Ghia et al observe that a proportion of patients with chronic lymphocytic leukemia (CLL) harbor mutations in genes involved in the Hedgehog (Hh) pathway resulting in expression of glioma-associated oncogene homolog 1 (GLI1). They also find that GLI1 is expressed in CLL cells without evidence of Hh mutations and that the high GLI1 levels correlate with disease progression.

This record has no associated files available for download.

More information

Accepted/In Press date: 1 April 2016
e-pub ahead of print date: 20 June 2019
Published date: 20 June 2019

Identifiers

Local EPrints ID: 434686
URI: http://eprints.soton.ac.uk/id/eprint/434686
ISSN: 0006-4971
PURE UUID: 34f64fb4-b3c0-4bd2-b444-8f51c80dfbaa
ORCID for Francesco Forconi: ORCID iD orcid.org/0000-0002-2211-1831

Catalogue record

Date deposited: 04 Oct 2019 16:30
Last modified: 16 Mar 2024 04:09

Export record

Altmetrics

Contributors

Author: Giorgia Chiodin

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×