Clinical characteristics of the Wessex AsThma CoHort of difficult asthma (WATCH)
Clinical characteristics of the Wessex AsThma CoHort of difficult asthma (WATCH)
Background: The Wessex AsThma CoHort of difficult asthma (WATCH) is a large prospective observational cohort study established at University Hospital Southampton (UHS) UK in 2015. Patients are enrolled from the UHS tertiary difficult asthma clinic. Aim: WATCH aims to improve understanding of the nature of difficult asthma in clinical practice. Here we report enrolment clinical characteristics. Methods: Patients undergo extensive clinical characterisation and phenotyping at enrolment using collated historical data plus objective clinical measurements. 380 patients have been enrolled to date with annual follow-up thereafter. Results: (as below) Conclusion: The cohort predominantly consists of female, middle-aged, atopic and obese patients whose disease often began before adulthood. The cohort showed high prevalence for maintenance oral steroids and omalizumab. WATCH provides a well-characterised cohort of patients to facilitate real-life difficult asthma research.
Mistry, Heena
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Azim, Adnan
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Harvey, Matt A E
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Thirlwall, Yvette
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Barber, Clair
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Haitchi, Hans Michael
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Newell, Colin
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Djukanovic, Ratko
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Howarth, Peter H
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Kurukulaaratchy, Ramesh J
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Mistry, Heena
216f0018-b071-406c-9b66-0e025ca959a7
Azim, Adnan
87c31e0e-c9bf-4258-9ae9-889e2382e7ba
Harvey, Matt A E
ea91a792-4966-41ca-9638-3c408d44cb2e
Thirlwall, Yvette
382d3468-33f2-44eb-91af-64fd9b5d8f07
Barber, Clair
ff31b460-34c3-466c-90e4-f70b3e954c82
Haitchi, Hans Michael
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Newell, Colin
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Djukanovic, Ratko
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Howarth, Peter H
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Kurukulaaratchy, Ramesh J
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Mistry, Heena, Azim, Adnan, Harvey, Matt A E, Thirlwall, Yvette, Barber, Clair, Haitchi, Hans Michael, Newell, Colin, Djukanovic, Ratko, Howarth, Peter H and Kurukulaaratchy, Ramesh J
(2018)
Clinical characteristics of the Wessex AsThma CoHort of difficult asthma (WATCH).
European Respiratory Journal, 52 (Supplement 62).
(doi:10.1183/13993003.congress-2018.pa1085).
Record type:
Meeting abstract
Abstract
Background: The Wessex AsThma CoHort of difficult asthma (WATCH) is a large prospective observational cohort study established at University Hospital Southampton (UHS) UK in 2015. Patients are enrolled from the UHS tertiary difficult asthma clinic. Aim: WATCH aims to improve understanding of the nature of difficult asthma in clinical practice. Here we report enrolment clinical characteristics. Methods: Patients undergo extensive clinical characterisation and phenotyping at enrolment using collated historical data plus objective clinical measurements. 380 patients have been enrolled to date with annual follow-up thereafter. Results: (as below) Conclusion: The cohort predominantly consists of female, middle-aged, atopic and obese patients whose disease often began before adulthood. The cohort showed high prevalence for maintenance oral steroids and omalizumab. WATCH provides a well-characterised cohort of patients to facilitate real-life difficult asthma research.
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e-pub ahead of print date: 19 November 2018
Venue - Dates:
European Respiratory Society Annual congress, , Paris, France, 2018-09-15 - 2018-09-19
Identifiers
Local EPrints ID: 435577
URI: http://eprints.soton.ac.uk/id/eprint/435577
ISSN: 0903-1936
PURE UUID: f72670a5-9a96-492a-b770-29d5b8a52962
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Date deposited: 12 Nov 2019 17:30
Last modified: 17 Mar 2024 02:49
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Contributors
Author:
Heena Mistry
Author:
Adnan Azim
Author:
Matt A E Harvey
Author:
Yvette Thirlwall
Author:
Clair Barber
Author:
Hans Michael Haitchi
Author:
Colin Newell
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