The University of Southampton
University of Southampton Institutional Repository

Clinical characteristics of the Wessex AsThma CoHort of difficult asthma (WATCH)

Clinical characteristics of the Wessex AsThma CoHort of difficult asthma (WATCH)
Clinical characteristics of the Wessex AsThma CoHort of difficult asthma (WATCH)
Background: The Wessex AsThma CoHort of difficult asthma (WATCH) is a large prospective observational cohort study established at University Hospital Southampton (UHS) UK in 2015. Patients are enrolled from the UHS tertiary difficult asthma clinic. Aim: WATCH aims to improve understanding of the nature of difficult asthma in clinical practice. Here we report enrolment clinical characteristics. Methods: Patients undergo extensive clinical characterisation and phenotyping at enrolment using collated historical data plus objective clinical measurements. 380 patients have been enrolled to date with annual follow-up thereafter. Results: (as below) Conclusion: The cohort predominantly consists of female, middle-aged, atopic and obese patients whose disease often began before adulthood. The cohort showed high prevalence for maintenance oral steroids and omalizumab. WATCH provides a well-characterised cohort of patients to facilitate real-life difficult asthma research.
0903-1936
Mistry, Heena
216f0018-b071-406c-9b66-0e025ca959a7
Azim, Adnan
87c31e0e-c9bf-4258-9ae9-889e2382e7ba
Harvey, Matt A E
ea91a792-4966-41ca-9638-3c408d44cb2e
Thirlwall, Yvette
382d3468-33f2-44eb-91af-64fd9b5d8f07
Barber, Clair
ff31b460-34c3-466c-90e4-f70b3e954c82
Haitchi, Hans Michael
10a08979-c9d4-448a-8e4e-35cee89b0c7a
Newell, Colin
fd859e4b-b3a6-4722-b1de-2e52c8633899
Djukanovic, Ratko
d9a45ee7-6a80-4d84-a0ed-10962660a98d
Howarth, Peter H
ff19c8c4-86b0-4a88-8f76-b3d87f142a21
Kurukulaaratchy, Ramesh J
9c7b8105-2892-49f2-8775-54d4961e3e74
Mistry, Heena
216f0018-b071-406c-9b66-0e025ca959a7
Azim, Adnan
87c31e0e-c9bf-4258-9ae9-889e2382e7ba
Harvey, Matt A E
ea91a792-4966-41ca-9638-3c408d44cb2e
Thirlwall, Yvette
382d3468-33f2-44eb-91af-64fd9b5d8f07
Barber, Clair
ff31b460-34c3-466c-90e4-f70b3e954c82
Haitchi, Hans Michael
10a08979-c9d4-448a-8e4e-35cee89b0c7a
Newell, Colin
fd859e4b-b3a6-4722-b1de-2e52c8633899
Djukanovic, Ratko
d9a45ee7-6a80-4d84-a0ed-10962660a98d
Howarth, Peter H
ff19c8c4-86b0-4a88-8f76-b3d87f142a21
Kurukulaaratchy, Ramesh J
9c7b8105-2892-49f2-8775-54d4961e3e74

Mistry, Heena, Azim, Adnan, Harvey, Matt A E, Thirlwall, Yvette, Barber, Clair, Haitchi, Hans Michael, Newell, Colin, Djukanovic, Ratko, Howarth, Peter H and Kurukulaaratchy, Ramesh J (2018) Clinical characteristics of the Wessex AsThma CoHort of difficult asthma (WATCH). European Respiratory Journal, 52 (Supplement 62). (doi:10.1183/13993003.congress-2018.pa1085).

Record type: Meeting abstract

Abstract

Background: The Wessex AsThma CoHort of difficult asthma (WATCH) is a large prospective observational cohort study established at University Hospital Southampton (UHS) UK in 2015. Patients are enrolled from the UHS tertiary difficult asthma clinic. Aim: WATCH aims to improve understanding of the nature of difficult asthma in clinical practice. Here we report enrolment clinical characteristics. Methods: Patients undergo extensive clinical characterisation and phenotyping at enrolment using collated historical data plus objective clinical measurements. 380 patients have been enrolled to date with annual follow-up thereafter. Results: (as below) Conclusion: The cohort predominantly consists of female, middle-aged, atopic and obese patients whose disease often began before adulthood. The cohort showed high prevalence for maintenance oral steroids and omalizumab. WATCH provides a well-characterised cohort of patients to facilitate real-life difficult asthma research.

Full text not available from this repository.

More information

e-pub ahead of print date: 19 November 2018
Venue - Dates: European Respiratory Society Annual congress, France, 2018-09-15 - 2018-09-19

Identifiers

Local EPrints ID: 435577
URI: http://eprints.soton.ac.uk/id/eprint/435577
ISSN: 0903-1936
PURE UUID: f72670a5-9a96-492a-b770-29d5b8a52962
ORCID for Clair Barber: ORCID iD orcid.org/0000-0001-5335-5129
ORCID for Ratko Djukanovic: ORCID iD orcid.org/0000-0001-6039-5612

Catalogue record

Date deposited: 12 Nov 2019 17:30
Last modified: 16 May 2020 00:50

Export record

Altmetrics

Contributors

Author: Heena Mistry
Author: Adnan Azim
Author: Matt A E Harvey
Author: Yvette Thirlwall
Author: Clair Barber ORCID iD
Author: Hans Michael Haitchi
Author: Colin Newell
Author: Peter H Howarth

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×