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Lactate monitoring in droplet microfluidics: a cautionary tale in assay miniaturisation

Lactate monitoring in droplet microfluidics: a cautionary tale in assay miniaturisation
Lactate monitoring in droplet microfluidics: a cautionary tale in assay miniaturisation
We present the development of a droplet-based device for real-time continuous lactate measurement, highlighting how protocols from long-established homogeneous enzymatic assays require careful re-optimisation before their migration into miniaturised droplet-based microfluidics.
1759-9660
6119-6123
Leong, Chi Leng
2e4c1b7f-b864-439a-acb8-4ec81ee54eea
Coleman, Sharon
2653c332-2105-46b7-98ca-450d88a3aa9f
Nightingale, Adrian
4b51311d-c6c3-40d5-a13f-ab8917031ab3
Hassan, Sammer-Ul
8a5ae3f1-3451-4093-879e-85f40953da8b
Voegeli, David
e6f5d112-55b0-40c1-a6ad-8929a2d84a10
Boutelle, Martyn G.
71e1592c-2e38-4695-8104-b233cc615494
Niu, Xize
f3d964fb-23b4-45db-92fe-02426e4e76fa
Leong, Chi Leng
2e4c1b7f-b864-439a-acb8-4ec81ee54eea
Coleman, Sharon
2653c332-2105-46b7-98ca-450d88a3aa9f
Nightingale, Adrian
4b51311d-c6c3-40d5-a13f-ab8917031ab3
Hassan, Sammer-Ul
8a5ae3f1-3451-4093-879e-85f40953da8b
Voegeli, David
e6f5d112-55b0-40c1-a6ad-8929a2d84a10
Boutelle, Martyn G.
71e1592c-2e38-4695-8104-b233cc615494
Niu, Xize
f3d964fb-23b4-45db-92fe-02426e4e76fa

Leong, Chi Leng, Coleman, Sharon, Nightingale, Adrian, Hassan, Sammer-Ul, Voegeli, David, Boutelle, Martyn G. and Niu, Xize (2019) Lactate monitoring in droplet microfluidics: a cautionary tale in assay miniaturisation. Analytical Methods, 11 (48), 6119-6123. (doi:10.1039/C9AY02070E).

Record type: Article

Abstract

We present the development of a droplet-based device for real-time continuous lactate measurement, highlighting how protocols from long-established homogeneous enzymatic assays require careful re-optimisation before their migration into miniaturised droplet-based microfluidics.

Text
Lactate paper_PostReview2_clean - Accepted Manuscript
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More information

Accepted/In Press date: 16 November 2019
e-pub ahead of print date: 18 November 2019
Published date: 28 December 2019

Identifiers

Local EPrints ID: 435938
URI: http://eprints.soton.ac.uk/id/eprint/435938
ISSN: 1759-9660
PURE UUID: 167a2f8c-402f-42b6-a09a-d8333a127a28
ORCID for Sammer-Ul Hassan: ORCID iD orcid.org/0000-0002-0319-5814
ORCID for David Voegeli: ORCID iD orcid.org/0000-0003-3457-7177

Catalogue record

Date deposited: 28 Nov 2019 17:30
Last modified: 22 Nov 2021 07:50

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Contributors

Author: Chi Leng Leong
Author: Sharon Coleman
Author: David Voegeli ORCID iD
Author: Martyn G. Boutelle
Author: Xize Niu

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