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Lesson of the month 1: Beware the atypical presentation: eosinophilic granulomatosis with polyangiitis presenting as acute coronary syndrome

Lesson of the month 1: Beware the atypical presentation: eosinophilic granulomatosis with polyangiitis presenting as acute coronary syndrome
Lesson of the month 1: Beware the atypical presentation: eosinophilic granulomatosis with polyangiitis presenting as acute coronary syndrome

We describe the case of a 45-year-old woman presenting with troponin positive cardiac-sounding chest pain. An initial emergency angiogram demonstrated two vessel coronary disease, including a distal right coronary artery occlusion. No percutaneous coronary intervention was performed and the patient was treated medically. At re-presentation with further pain a few days later, coronary angiography demonstrated no significant coronary lesions. After consideration of other multisystem symptoms and raised eosinophil count, the patient was diagnosed with eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome) presenting with coronary arteritis. This case should remind physicians to be vigilant and to consider non-atherosclerotic causes of acute coronary syndrome presentation, which should not always result in a stent.

Acute Coronary Syndrome, Churg-Strauss Syndrome, Coronary Angiography, Female, Granulomatosis with Polyangiitis, Humans, Middle Aged
1470-2118
180-182
Schiefermueller, Juergen
dd22435f-ed1c-4d96-a87c-80b70e28c609
Alaour, Bashir
b7c4eaf2-53af-4ce0-88c9-68a0c163c49d
Calver, Alison
b10f84f4-e427-44e9-a349-754ca1371f25
Curzen, Nick
70f3ea49-51b1-418f-8e56-8210aef1abf4
Schiefermueller, Juergen
dd22435f-ed1c-4d96-a87c-80b70e28c609
Alaour, Bashir
b7c4eaf2-53af-4ce0-88c9-68a0c163c49d
Calver, Alison
b10f84f4-e427-44e9-a349-754ca1371f25
Curzen, Nick
70f3ea49-51b1-418f-8e56-8210aef1abf4

Schiefermueller, Juergen, Alaour, Bashir, Calver, Alison and Curzen, Nick (2017) Lesson of the month 1: Beware the atypical presentation: eosinophilic granulomatosis with polyangiitis presenting as acute coronary syndrome. Clinical Medicine, 17 (2), 180-182. (doi:10.7861/clinmedicine.17-2-180).

Record type: Article

Abstract

We describe the case of a 45-year-old woman presenting with troponin positive cardiac-sounding chest pain. An initial emergency angiogram demonstrated two vessel coronary disease, including a distal right coronary artery occlusion. No percutaneous coronary intervention was performed and the patient was treated medically. At re-presentation with further pain a few days later, coronary angiography demonstrated no significant coronary lesions. After consideration of other multisystem symptoms and raised eosinophil count, the patient was diagnosed with eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome) presenting with coronary arteritis. This case should remind physicians to be vigilant and to consider non-atherosclerotic causes of acute coronary syndrome presentation, which should not always result in a stent.

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More information

Published date: April 2017
Keywords: Acute Coronary Syndrome, Churg-Strauss Syndrome, Coronary Angiography, Female, Granulomatosis with Polyangiitis, Humans, Middle Aged

Identifiers

Local EPrints ID: 436093
URI: http://eprints.soton.ac.uk/id/eprint/436093
ISSN: 1470-2118
PURE UUID: 8cf27dd8-8182-4fed-97b0-d570fbdfce8d
ORCID for Nick Curzen: ORCID iD orcid.org/0000-0001-9651-7829

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Date deposited: 27 Nov 2019 17:30
Last modified: 17 Mar 2024 03:02

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Contributors

Author: Juergen Schiefermueller
Author: Bashir Alaour
Author: Alison Calver
Author: Nick Curzen ORCID iD

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