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Multiple cases with probable treponemal infection from 16th to 19th centuries Romania

Multiple cases with probable treponemal infection from 16th to 19th centuries Romania
Multiple cases with probable treponemal infection from 16th to 19th centuries Romania
In this paper, we describe pathological lesions identified in seven skeletons discovered in the Saint Sava necropolis in Bucharest, Romania, dating to the Late Medieval/Early Modern period. The pathological changes observed in the skeletons were analysed using macroscopic examination. Additionally, computed tomography scanning was performed on two individuals displaying advanced lesions on the cranial surface. For the differential diagnosis, we took into consideration treponemal infection, tuberculosis, osteomyelitis, leprosy, fluorosis, melorheostosis, hypertrophic pulmonary osteoarthropathy, Paget's disease and mycotic infection, along with the possibility of multiple afflictions occurring simultaneously. The morphology and distribution of the lesions are suggestive of treponematosis, which, to our knowledge, makes this the first case of this disease on the Romanian territory in archaeological populations.
infectious disease, late medieval, Romania, treponematosis, venereal syphilis
1047-482X
563-573
Radu, Claudia
03de186c-1e53-4a48-a478-5017c2ec2262
Andreica, L.
c114e35d-16f8-43e6-8abd-a92b097a7204
Constantinescu, M.
86d29153-0432-4351-9e3a-67c270589eca
Soficaru, A.
2fbb819e-7c20-47dc-8fdb-c60ca26c4623
Radu, Claudia
03de186c-1e53-4a48-a478-5017c2ec2262
Andreica, L.
c114e35d-16f8-43e6-8abd-a92b097a7204
Constantinescu, M.
86d29153-0432-4351-9e3a-67c270589eca
Soficaru, A.
2fbb819e-7c20-47dc-8fdb-c60ca26c4623

Radu, Claudia, Andreica, L., Constantinescu, M. and Soficaru, A. (2016) Multiple cases with probable treponemal infection from 16th to 19th centuries Romania. International Journal of Osteoarchaeology, 26 (4), 563-573. (doi:10.1002/oa.2444).

Record type: Article

Abstract

In this paper, we describe pathological lesions identified in seven skeletons discovered in the Saint Sava necropolis in Bucharest, Romania, dating to the Late Medieval/Early Modern period. The pathological changes observed in the skeletons were analysed using macroscopic examination. Additionally, computed tomography scanning was performed on two individuals displaying advanced lesions on the cranial surface. For the differential diagnosis, we took into consideration treponemal infection, tuberculosis, osteomyelitis, leprosy, fluorosis, melorheostosis, hypertrophic pulmonary osteoarthropathy, Paget's disease and mycotic infection, along with the possibility of multiple afflictions occurring simultaneously. The morphology and distribution of the lesions are suggestive of treponematosis, which, to our knowledge, makes this the first case of this disease on the Romanian territory in archaeological populations.

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More information

e-pub ahead of print date: 25 February 2015
Published date: 25 July 2016
Keywords: infectious disease, late medieval, Romania, treponematosis, venereal syphilis

Identifiers

Local EPrints ID: 436104
URI: http://eprints.soton.ac.uk/id/eprint/436104
ISSN: 1047-482X
PURE UUID: 1e8eaf56-1fe5-4189-a190-eb6c43493518
ORCID for A. Soficaru: ORCID iD orcid.org/0000-0001-8658-6695

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Date deposited: 27 Nov 2019 17:30
Last modified: 03 Dec 2019 01:22

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Contributors

Author: Claudia Radu
Author: L. Andreica
Author: M. Constantinescu
Author: A. Soficaru ORCID iD

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