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Determinants of initiation, implementation, and discontinuation of amoxicillin by adults with acute cough in primary care

Determinants of initiation, implementation, and discontinuation of amoxicillin by adults with acute cough in primary care
Determinants of initiation, implementation, and discontinuation of amoxicillin by adults with acute cough in primary care
Aim: To investigate the determinants of adherence to amoxicillin in patients with acute lower respiratory tract infection. Materials and methods: Three European data sets were used. Adherence data were collected using self-reported diaries. Candidate determinants included factors relating to patient, condition, therapy, health care system/provider, and the study in which the patient participated. Logistic and Cox regression models were used to investigate the determinants of initiation, implementation, and discontinuation of amoxicillin. Results: Although initiation differed across samples, implementation and discontinuation were similar. Determinants of initiation were days waited before consulting, duration of prescription, and being in a country where a doctor-issued sick certificate is required for being off work for
adherence, antibiotics, general practice, determinants
561-569
Gillespie, David
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Farewell, Daniel
bb0b8839-4fd9-418d-976f-f732002b2f8d
Brookes-Howell, Lucy
307c5275-082d-4586-ba9d-461527607164
Butler, Christopher
8bf4cace-c34a-4b65-838f-29c2be91e434
Coenen, Samuel
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Francis, Nicholas Andrew
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Little, Paul
1bf2d1f7-200c-47a5-ab16-fe5a8756a777
Stuart, Beth
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Verheij, Theo
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Hood, Kerenza
af7cf839-ca85-4ea9-83c3-3dd31be88b32
Gillespie, David
a796af31-39b7-47b9-840f-c893e43013dd
Farewell, Daniel
bb0b8839-4fd9-418d-976f-f732002b2f8d
Brookes-Howell, Lucy
307c5275-082d-4586-ba9d-461527607164
Butler, Christopher
8bf4cace-c34a-4b65-838f-29c2be91e434
Coenen, Samuel
3d0dc4e0-e5ba-4d66-ba92-15900ccc551e
Francis, Nicholas Andrew
9b610883-605c-4fee-871d-defaa86ccf8e
Little, Paul
1bf2d1f7-200c-47a5-ab16-fe5a8756a777
Stuart, Beth
626862fc-892b-4f6d-9cbb-7a8d7172b209
Verheij, Theo
772e019f-486f-4a64-9260-bac6446a85d2
Hood, Kerenza
af7cf839-ca85-4ea9-83c3-3dd31be88b32

Gillespie, David, Farewell, Daniel, Brookes-Howell, Lucy, Butler, Christopher, Coenen, Samuel, Francis, Nicholas Andrew, Little, Paul, Stuart, Beth, Verheij, Theo and Hood, Kerenza (2017) Determinants of initiation, implementation, and discontinuation of amoxicillin by adults with acute cough in primary care. Patient Preference and Adherence, 2017 (11), 561-569. (doi:10.2147/PPA.S119256).

Record type: Article

Abstract

Aim: To investigate the determinants of adherence to amoxicillin in patients with acute lower respiratory tract infection. Materials and methods: Three European data sets were used. Adherence data were collected using self-reported diaries. Candidate determinants included factors relating to patient, condition, therapy, health care system/provider, and the study in which the patient participated. Logistic and Cox regression models were used to investigate the determinants of initiation, implementation, and discontinuation of amoxicillin. Results: Although initiation differed across samples, implementation and discontinuation were similar. Determinants of initiation were days waited before consulting, duration of prescription, and being in a country where a doctor-issued sick certificate is required for being off work for

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PPA-119256-determinants-of-initiation--implementation--and-discontinuat_031517 - Version of Record
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Accepted/In Press date: 9 November 2016
Published date: 15 March 2017
Keywords: adherence, antibiotics, general practice, determinants

Identifiers

Local EPrints ID: 436138
URI: http://eprints.soton.ac.uk/id/eprint/436138
PURE UUID: 17903dfe-da93-4a44-b3a2-85a3ecdf6b47
ORCID for Nicholas Andrew Francis: ORCID iD orcid.org/0000-0001-8939-7312
ORCID for Beth Stuart: ORCID iD orcid.org/0000-0001-5432-7437

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Date deposited: 29 Nov 2019 17:30
Last modified: 09 Jan 2022 04:08

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Contributors

Author: David Gillespie
Author: Daniel Farewell
Author: Lucy Brookes-Howell
Author: Christopher Butler
Author: Samuel Coenen
Author: Paul Little
Author: Beth Stuart ORCID iD
Author: Theo Verheij
Author: Kerenza Hood

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