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Extrusion-based 3D printing technologies for 3D scaffold engineering

Extrusion-based 3D printing technologies for 3D scaffold engineering
Extrusion-based 3D printing technologies for 3D scaffold engineering
Different fabrication methods from traditional chemical engineering methods to advanced additive manufacturing (AM) are used for fabrication of tissue engineering (TE) scaffolds. The traditional techniques are subjected to limitations such as manual intervention, and inconsistent and inflexible processing procedures. In addition, the traditional techniques usually cannot control pore size, pore geometry, and spatial distribution of pores properly. To complement these limitations, there has been a trend in recent years to fabricate TE scaffolds using AM processes directly (3D printing of final scaffold) or indirectly (making negative scaffold to be used as a mold). In particular, extrusion-based AM systems have been widely used for fabrication of TE scaffolds due to their ability of processing different biomaterials, their possibility of manufacturing scaffolds in a cell-friendly environment, their high reproducibility and flexibility, and their simple process control in comparison with other AM techniques. In this chapter, the applications of extrusion-based 3D printing techniques are reviewed. In addition, an in-depth discussion on solvent-based extrusion freeforming (SEF) method, recent advances in printing bioceramic scaffolds, and its new application to make polyether-ether-ketone (PEEK)-based composites are presented.
Additive manufacturing (AM), 3D printing, tissue engineering (TE), extrusion-based 3D printing
235-254
Elsevier
Vaezi, Mohammad
828e14c1-3236-4153-8f69-3837233f48ed
Zhong, Gaoyan
4122f394-9978-4435-874b-5e8356d19a31
Kalami, Hamed
d920d965-7ddc-435b-a580-399763326dd5
Yang, Shoufeng
e0018adf-8123-4a54-b8dd-306c10ca48f1
Vaezi, Mohammad
828e14c1-3236-4153-8f69-3837233f48ed
Zhong, Gaoyan
4122f394-9978-4435-874b-5e8356d19a31
Kalami, Hamed
d920d965-7ddc-435b-a580-399763326dd5
Yang, Shoufeng
e0018adf-8123-4a54-b8dd-306c10ca48f1

Vaezi, Mohammad, Zhong, Gaoyan, Kalami, Hamed and Yang, Shoufeng (2018) Extrusion-based 3D printing technologies for 3D scaffold engineering. In, Functional 3D Tissue Engineering Scaffolds. Elsevier, pp. 235-254. (doi:10.1016/B978-0-08-100979-6.00010-0).

Record type: Book Section

Abstract

Different fabrication methods from traditional chemical engineering methods to advanced additive manufacturing (AM) are used for fabrication of tissue engineering (TE) scaffolds. The traditional techniques are subjected to limitations such as manual intervention, and inconsistent and inflexible processing procedures. In addition, the traditional techniques usually cannot control pore size, pore geometry, and spatial distribution of pores properly. To complement these limitations, there has been a trend in recent years to fabricate TE scaffolds using AM processes directly (3D printing of final scaffold) or indirectly (making negative scaffold to be used as a mold). In particular, extrusion-based AM systems have been widely used for fabrication of TE scaffolds due to their ability of processing different biomaterials, their possibility of manufacturing scaffolds in a cell-friendly environment, their high reproducibility and flexibility, and their simple process control in comparison with other AM techniques. In this chapter, the applications of extrusion-based 3D printing techniques are reviewed. In addition, an in-depth discussion on solvent-based extrusion freeforming (SEF) method, recent advances in printing bioceramic scaffolds, and its new application to make polyether-ether-ketone (PEEK)-based composites are presented.

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More information

e-pub ahead of print date: 6 October 2017
Published date: 2018
Keywords: Additive manufacturing (AM), 3D printing, tissue engineering (TE), extrusion-based 3D printing

Identifiers

Local EPrints ID: 436340
URI: http://eprints.soton.ac.uk/id/eprint/436340
PURE UUID: 96b90f68-536a-473d-a798-bd157a6ac6d9
ORCID for Shoufeng Yang: ORCID iD orcid.org/0000-0002-3888-3211

Catalogue record

Date deposited: 06 Dec 2019 17:30
Last modified: 17 Dec 2019 01:41

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