The University of Southampton
University of Southampton Institutional Repository
Warning ePrints Soton is experiencing an issue with some file downloads not being available. We are working hard to fix this. Please bear with us.

A feasibility study of a psycho‐educational support intervention for men with prostate cancer on active surveillance

A feasibility study of a psycho‐educational support intervention for men with prostate cancer on active surveillance
A feasibility study of a psycho‐educational support intervention for men with prostate cancer on active surveillance
Background
PROACTIVE is a psycho‐educational support intervention for prostate cancer patients managed on Active Surveillance. PROACTIVE is composed of two interdependent components: group workshops and internet‐delivered information modules.

Aims
We conducted a feasibility study to determine the practicality of delivering PROACTIVE at two prostate cancer centres.

Methods and Results
The feasibility study was a mixed‐methods randomized parallel‐group exploratory trial. Participants were randomised using a ratio of 3:1 PROACTIVE group to treatment as usual. Qualitative semi‐structured interviews and quantitative measures were completed at baseline, intervention completion (week 6), and at 6‐month follow‐up. Interview transcripts were analysed thematically using Framework analysis. Descriptive statistics were used to examine recruitment and retention rates and changing trends in outcome measures. Most aspects of the research design and PROACTIVE intervention were acceptable to those participating in the study. In particular, participants valued the opportunity to share and discuss experiences with other prostate cancer patients on Active Surveillance and receive detailed authoritative information. However, three issues were identified: (a) a low response rate (13 participants recruited, response rate 16%), (b) low utilisation of internet delivered information modules, (c) self‐perceived low levels of anxiety amongst participants with the majority perceiving their cancer as not impacting on their day‐to‐day life or causing anxiety.

Conclusions
Due to these significant research design issues, it is not recommended PROACTIVE be evaluated in a large‐scale randomised controlled trial. Further research is required to explore the impact of Active Surveillance on anxiety amongst men with localized prostate cancer managed by Active Surveillance.
2573-8348
1-8
Hughes, John G.
285870fc-1a6a-437a-a13b-7ba0ae392413
Leydon, Geraldine M.
c5cdaff5-0fa1-4d38-b575-b97c2892ec40
Watts, Sam
f399ac6d-e114-4960-944a-9c2a93607190
Hughes, Stephanie
a6d39500-67ff-4d7a-a1dc-8e42f80945ff
Brindle, Lucy A.
17158264-2a99-4786-afc0-30990240436c
Arden‐close, Emily
476eebfb-e256-474b-8351-09db1efdeab5
Bacon, Roger
690ac754-376e-4148-b05b-1c97ff278a52
Birch, Brian
8a94cd36-d429-4ab4-82a6-a376b4d4e10f
Carballo, Lallita
03c9be1b-4589-49db-a628-37bc6830d3c4
Plant, Hilary
f3aafaf2-a3c0-483d-8eee-6d6271f11aaa
Moore, Caroline M.
87ccbdc5-40b6-41b5-8639-46f3f04896e9
Stuart, Beth
626862fc-892b-4f6d-9cbb-7a8d7172b209
Yao, Guiqing
d777f84c-cf3d-4fad-bbc1-ea01dec01695
Lewith, George
0fc483fa-f17b-47c5-94d9-5c15e65a7625
Richardson, Alison
3db30680-aa47-43a5-b54d-62d10ece17b7
Hughes, John G.
285870fc-1a6a-437a-a13b-7ba0ae392413
Leydon, Geraldine M.
c5cdaff5-0fa1-4d38-b575-b97c2892ec40
Watts, Sam
f399ac6d-e114-4960-944a-9c2a93607190
Hughes, Stephanie
a6d39500-67ff-4d7a-a1dc-8e42f80945ff
Brindle, Lucy A.
17158264-2a99-4786-afc0-30990240436c
Arden‐close, Emily
476eebfb-e256-474b-8351-09db1efdeab5
Bacon, Roger
690ac754-376e-4148-b05b-1c97ff278a52
Birch, Brian
8a94cd36-d429-4ab4-82a6-a376b4d4e10f
Carballo, Lallita
03c9be1b-4589-49db-a628-37bc6830d3c4
Plant, Hilary
f3aafaf2-a3c0-483d-8eee-6d6271f11aaa
Moore, Caroline M.
87ccbdc5-40b6-41b5-8639-46f3f04896e9
Stuart, Beth
626862fc-892b-4f6d-9cbb-7a8d7172b209
Yao, Guiqing
d777f84c-cf3d-4fad-bbc1-ea01dec01695
Lewith, George
0fc483fa-f17b-47c5-94d9-5c15e65a7625
Richardson, Alison
3db30680-aa47-43a5-b54d-62d10ece17b7

Hughes, John G., Leydon, Geraldine M., Watts, Sam, Hughes, Stephanie, Brindle, Lucy A., Arden‐close, Emily, Bacon, Roger, Birch, Brian, Carballo, Lallita, Plant, Hilary, Moore, Caroline M., Stuart, Beth, Yao, Guiqing, Lewith, George and Richardson, Alison (2019) A feasibility study of a psycho‐educational support intervention for men with prostate cancer on active surveillance. Cancer Reports, 1-8. (doi:10.1002/cnr2.1230).

Record type: Article

Abstract

Background
PROACTIVE is a psycho‐educational support intervention for prostate cancer patients managed on Active Surveillance. PROACTIVE is composed of two interdependent components: group workshops and internet‐delivered information modules.

Aims
We conducted a feasibility study to determine the practicality of delivering PROACTIVE at two prostate cancer centres.

Methods and Results
The feasibility study was a mixed‐methods randomized parallel‐group exploratory trial. Participants were randomised using a ratio of 3:1 PROACTIVE group to treatment as usual. Qualitative semi‐structured interviews and quantitative measures were completed at baseline, intervention completion (week 6), and at 6‐month follow‐up. Interview transcripts were analysed thematically using Framework analysis. Descriptive statistics were used to examine recruitment and retention rates and changing trends in outcome measures. Most aspects of the research design and PROACTIVE intervention were acceptable to those participating in the study. In particular, participants valued the opportunity to share and discuss experiences with other prostate cancer patients on Active Surveillance and receive detailed authoritative information. However, three issues were identified: (a) a low response rate (13 participants recruited, response rate 16%), (b) low utilisation of internet delivered information modules, (c) self‐perceived low levels of anxiety amongst participants with the majority perceiving their cancer as not impacting on their day‐to‐day life or causing anxiety.

Conclusions
Due to these significant research design issues, it is not recommended PROACTIVE be evaluated in a large‐scale randomised controlled trial. Further research is required to explore the impact of Active Surveillance on anxiety amongst men with localized prostate cancer managed by Active Surveillance.

Text
A feasibility study of a psycho-educational support intervention for men with prostate cancer on active surveillance
Restricted to Repository staff only
Request a copy

More information

Accepted/In Press date: 11 September 2019
e-pub ahead of print date: 9 December 2019

Identifiers

Local EPrints ID: 436592
URI: http://eprints.soton.ac.uk/id/eprint/436592
ISSN: 2573-8348
PURE UUID: d201b06c-8e81-4e4f-8426-7035cd85f1c8
ORCID for Geraldine M. Leydon: ORCID iD orcid.org/0000-0001-5986-3300
ORCID for Lucy A. Brindle: ORCID iD orcid.org/0000-0002-8933-3754
ORCID for Beth Stuart: ORCID iD orcid.org/0000-0001-5432-7437
ORCID for Alison Richardson: ORCID iD orcid.org/0000-0003-3127-5755

Catalogue record

Date deposited: 17 Dec 2019 17:30
Last modified: 26 Nov 2021 02:55

Export record

Altmetrics

Contributors

Author: John G. Hughes
Author: Sam Watts
Author: Lucy A. Brindle ORCID iD
Author: Emily Arden‐close
Author: Roger Bacon
Author: Brian Birch
Author: Lallita Carballo
Author: Hilary Plant
Author: Caroline M. Moore
Author: Beth Stuart ORCID iD
Author: Guiqing Yao
Author: George Lewith

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×