Rapid syndromic molecular testing in pneumonia: the current landscape and future potential
Rapid syndromic molecular testing in pneumonia: the current landscape and future potential
Community acquired pneumonia (CAP), hospital-acquired pneumonia (HAP) and ventilator associated pneumonia (VAP) are all associated with significant mortality and cause huge expense to health care services around the world. Early, appropriate antimicrobial therapy is crucial for effective treatment. Syndromic diagnostic testing using novel, rapid multiplexed molecular platforms represents a new opportunity for rapidly targeted antimicrobial therapy to improve patient outcomes and facilitate antibiotic stewardship. In this article we review the currently available testing platforms and discuss the potential benefits and pitfalls of rapid testing in pneumonia.
Poole, Stephen
440d7904-ab72-469c-892b-c910cd1cb19b
Clark, Tristan
712ec18e-613c-45df-a013-c8a22834e14f
Poole, Stephen
440d7904-ab72-469c-892b-c910cd1cb19b
Clark, Tristan
712ec18e-613c-45df-a013-c8a22834e14f
Poole, Stephen and Clark, Tristan
(2019)
Rapid syndromic molecular testing in pneumonia: the current landscape and future potential.
Journal of Infection.
(doi:10.1016/j.jinf.2019.11.021).
Abstract
Community acquired pneumonia (CAP), hospital-acquired pneumonia (HAP) and ventilator associated pneumonia (VAP) are all associated with significant mortality and cause huge expense to health care services around the world. Early, appropriate antimicrobial therapy is crucial for effective treatment. Syndromic diagnostic testing using novel, rapid multiplexed molecular platforms represents a new opportunity for rapidly targeted antimicrobial therapy to improve patient outcomes and facilitate antibiotic stewardship. In this article we review the currently available testing platforms and discuss the potential benefits and pitfalls of rapid testing in pneumonia.
Text
1-s2.0-S016344531930372X-main
- Accepted Manuscript
More information
Accepted/In Press date: 29 November 2019
e-pub ahead of print date: 3 December 2019
Identifiers
Local EPrints ID: 436774
URI: http://eprints.soton.ac.uk/id/eprint/436774
ISSN: 0163-4453
PURE UUID: f2e2faa5-3f73-4829-9406-684fe82c3ad5
Catalogue record
Date deposited: 07 Jan 2020 17:32
Last modified: 17 Mar 2024 05:07
Export record
Altmetrics
Contributors
Author:
Stephen Poole
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
