The University of Southampton
University of Southampton Institutional Repository

Examining the effectiveness of general practitioner and nurse promotion of electronic cigarettes versus standard care for smoking reduction and abstinence in hardcore smokers with smoking-related chronic disease: protocol for a randomised controlled trial

Examining the effectiveness of general practitioner and nurse promotion of electronic cigarettes versus standard care for smoking reduction and abstinence in hardcore smokers with smoking-related chronic disease: protocol for a randomised controlled trial
Examining the effectiveness of general practitioner and nurse promotion of electronic cigarettes versus standard care for smoking reduction and abstinence in hardcore smokers with smoking-related chronic disease: protocol for a randomised controlled trial
Background
Despite the clear harm associated with smoking tobacco, many people with smoking-related chronic diseases or serious mental illnesses (SMI) are unwilling or unable to stop smoking. In many cases, these smokers have tried and exhausted all methods to stop smoking and yet clinicians are repeatedly mandated to offer them during routine consultations. Providing nicotine through electronic cigarettes (e-cigarettes), may reduce the adverse health consequences associated with tobacco smoking, but these are not currently offered. The aim of this study is to examine the feasibility, acceptability, and effectiveness of general practitioners (GPs) and nurses delivering a brief advice intervention on e-cigarettes and offering an e-cigarette starter pack and patient support resources compared with standard care in smokers with smoking-related chronic diseases or SMI who are unwilling to stop smoking.

Methods
This is an individually randomised, blinded, two-arm trial. Smokers with a smoking-related chronic condition or SMI with no intention of stopping smoking will be recruited throughprimary care registers. Eligible participants will be randomised to one of two groups if they decline standard care for stopping smoking: a control group who will receive no additional support beyond standard care, or an intervention group who will receive GP or nurse-led brief advice about e-cigarettes, an e-cigarette starter pack with accompanying practical support booklet, and telephone support from experienced vapers and online video tutorials. The primary outcome measures will be smoking reduction, measured through changes in cigarettes per day and 7-day point-prevalence abstinence at two months. Secondary outcomes include smoking reduction, 7-day point-prevalence abstinence and prolonged abstinence at eight months. Other outcomes include patient recruitment and follow-up, patient uptake and use of e-cigarettes, nicotine intake, contamination of randomisation and practitioner adherence to the delivery of the intervention. Qualitative interviews will be conducted in a subsample of practitioners, patients and the vape team to garner their reactions to the programme.

Discussion
This is the first randomised controlled trial to investigate whether e-cigarette provision alongside a brief intervention delivered by practitioners leads to reduced smoking and abstinence among smokers with smoking-related chronic diseases or SMI.
Smoking, Tobacco, Electronic Cigarettes, Cessation, Quitting, Addiction, Treatment, Primary Care
1745-6215
Begh, Rachna
0fbb3a27-9c5c-4478-8b79-4a446af4f694
Coleman, Tim
f35d7107-efec-4c58-a9f5-bbb9cd3ff35c
Yardley, Lucy
64be42c4-511d-484d-abaa-f8813452a22e
Barnes, Rebecca
ff01993c-6ae3-4d1e-9ee0-30d0bc9d0720
Naughton, Felix
31fe7ac9-9faa-4033-ac89-cf7dd6a947e4
Gilbert, Hazel
ac6d2ea2-4360-46f4-80b9-d1c5061dbbce
Ferrey, Anne
38b7fff0-a408-47f5-93ad-069d2678c8d1
Madigan, Claire
d16fab51-6777-48a4-bfbc-7b5f414131bb
Williams, Nicola
7f429fa6-6971-4ed3-8886-03f2ab01e3d1
Hamilton, Louisa
c0d74cff-4430-4d4d-a19a-2cc4eb33d231
Warren, Yolanda
8c357c6a-e2a7-4461-8b7f-087b319896e5
Grabey, Jenna
ae75693d-6da5-4834-bdcb-771ec029c256
Clark, Miranda
0379179a-3886-453c-95b0-5e856510e612
Dickinson, Anne
a72b705b-8901-4041-b8d2-fdf19ef4755b
Aveyard, Paul
52ed3854-13ad-4680-8d49-408a81a558d4
Begh, Rachna
0fbb3a27-9c5c-4478-8b79-4a446af4f694
Coleman, Tim
f35d7107-efec-4c58-a9f5-bbb9cd3ff35c
Yardley, Lucy
64be42c4-511d-484d-abaa-f8813452a22e
Barnes, Rebecca
ff01993c-6ae3-4d1e-9ee0-30d0bc9d0720
Naughton, Felix
31fe7ac9-9faa-4033-ac89-cf7dd6a947e4
Gilbert, Hazel
ac6d2ea2-4360-46f4-80b9-d1c5061dbbce
Ferrey, Anne
38b7fff0-a408-47f5-93ad-069d2678c8d1
Madigan, Claire
d16fab51-6777-48a4-bfbc-7b5f414131bb
Williams, Nicola
7f429fa6-6971-4ed3-8886-03f2ab01e3d1
Hamilton, Louisa
c0d74cff-4430-4d4d-a19a-2cc4eb33d231
Warren, Yolanda
8c357c6a-e2a7-4461-8b7f-087b319896e5
Grabey, Jenna
ae75693d-6da5-4834-bdcb-771ec029c256
Clark, Miranda
0379179a-3886-453c-95b0-5e856510e612
Dickinson, Anne
a72b705b-8901-4041-b8d2-fdf19ef4755b
Aveyard, Paul
52ed3854-13ad-4680-8d49-408a81a558d4

Begh, Rachna, Coleman, Tim, Yardley, Lucy, Barnes, Rebecca, Naughton, Felix, Gilbert, Hazel, Ferrey, Anne, Madigan, Claire, Williams, Nicola, Hamilton, Louisa, Warren, Yolanda, Grabey, Jenna, Clark, Miranda, Dickinson, Anne and Aveyard, Paul (2019) Examining the effectiveness of general practitioner and nurse promotion of electronic cigarettes versus standard care for smoking reduction and abstinence in hardcore smokers with smoking-related chronic disease: protocol for a randomised controlled trial. Trials, 20, [659]. (doi:10.1186/s13063-019-3850-1).

Record type: Article

Abstract

Background
Despite the clear harm associated with smoking tobacco, many people with smoking-related chronic diseases or serious mental illnesses (SMI) are unwilling or unable to stop smoking. In many cases, these smokers have tried and exhausted all methods to stop smoking and yet clinicians are repeatedly mandated to offer them during routine consultations. Providing nicotine through electronic cigarettes (e-cigarettes), may reduce the adverse health consequences associated with tobacco smoking, but these are not currently offered. The aim of this study is to examine the feasibility, acceptability, and effectiveness of general practitioners (GPs) and nurses delivering a brief advice intervention on e-cigarettes and offering an e-cigarette starter pack and patient support resources compared with standard care in smokers with smoking-related chronic diseases or SMI who are unwilling to stop smoking.

Methods
This is an individually randomised, blinded, two-arm trial. Smokers with a smoking-related chronic condition or SMI with no intention of stopping smoking will be recruited throughprimary care registers. Eligible participants will be randomised to one of two groups if they decline standard care for stopping smoking: a control group who will receive no additional support beyond standard care, or an intervention group who will receive GP or nurse-led brief advice about e-cigarettes, an e-cigarette starter pack with accompanying practical support booklet, and telephone support from experienced vapers and online video tutorials. The primary outcome measures will be smoking reduction, measured through changes in cigarettes per day and 7-day point-prevalence abstinence at two months. Secondary outcomes include smoking reduction, 7-day point-prevalence abstinence and prolonged abstinence at eight months. Other outcomes include patient recruitment and follow-up, patient uptake and use of e-cigarettes, nicotine intake, contamination of randomisation and practitioner adherence to the delivery of the intervention. Qualitative interviews will be conducted in a subsample of practitioners, patients and the vape team to garner their reactions to the programme.

Discussion
This is the first randomised controlled trial to investigate whether e-cigarette provision alongside a brief intervention delivered by practitioners leads to reduced smoking and abstinence among smokers with smoking-related chronic diseases or SMI.

Text
Examining the effectiveness_BEGH_Trials - Accepted Manuscript
Restricted to Repository staff only
Request a copy
Text
documentrb - Version of Record
Available under License Creative Commons Attribution.
Download (1MB)

More information

Accepted/In Press date: 25 October 2019
e-pub ahead of print date: 28 November 2019
Published date: 28 November 2019
Keywords: Smoking, Tobacco, Electronic Cigarettes, Cessation, Quitting, Addiction, Treatment, Primary Care

Identifiers

Local EPrints ID: 436889
URI: http://eprints.soton.ac.uk/id/eprint/436889
ISSN: 1745-6215
PURE UUID: 1f044fde-cf04-47b6-8cb0-b54ee7fb39e3
ORCID for Lucy Yardley: ORCID iD orcid.org/0000-0002-3853-883X

Catalogue record

Date deposited: 13 Jan 2020 17:32
Last modified: 07 Oct 2020 01:42

Export record

Altmetrics

Contributors

Author: Rachna Begh
Author: Tim Coleman
Author: Lucy Yardley ORCID iD
Author: Rebecca Barnes
Author: Felix Naughton
Author: Hazel Gilbert
Author: Anne Ferrey
Author: Claire Madigan
Author: Nicola Williams
Author: Louisa Hamilton
Author: Yolanda Warren
Author: Jenna Grabey
Author: Miranda Clark
Author: Anne Dickinson
Author: Paul Aveyard

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×