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Morbidity following complex EVAR

Morbidity following complex EVAR
Morbidity following complex EVAR
Objectives: patterns of morbidity are poorly characterized for patients undergoing complex EVAR. Evidence for complex endografts is based on case series and morbidity is often poorly reported. Multi organ dysfunction is described but the pathological events triggering this are uncertain. We hypothesised that early postoperative cardiac morbidity occurs as part of multi-organ dysfunction rather than as an isolated ischaemic event.

Methods: a prospective analysis of 41 patients undergoing complex EVAR was undertaken. Primary endpoint was development of cardiac morbidity, on postoperative day 3.

Results: 8 patients underwent thoracoabdominal, 29 juxtarenal fenestrated and 4 iliac branched graft AAA repair. There were 5 deaths, 3 of which were in emergency cases. The most common postoperative morbidities on day 5 were renal (50% of inpatients), respiratory (44%), gastrointestinal (25%) and cardiac (19%). Occurrence of cardiac morbidity on day 3 was associated with increased total morbidity on days 3, 5, 8 and 15 (P=.04).

Conclusions: complex EVAR patients suffer non-cardiac morbidity in line with major non-vascular surgery. Early postoperative cardiac morbidity is associated with multi-organ dysfunction in this population indicating a more global pathology. This highlights the need for further study into the aetiology of cardiac injury in this group.
1743-9191
576-576
Cross, Jane
5b11227f-2b5e-4da7-9a63-194534d32279
Edwards, Mark
818201d5-7636-4292-9af8-7dd8bcd1fcb5
Harrison, Seamus
ba3377b5-c7ea-40df-81ee-e00bb6fda889
Richards, Toby
fffe064a-a2c6-4d35-8ea9-128eda18f7fa
Ackland, Gareth
bb1ef7dd-0a25-4c8c-9963-9b216115468d
Cross, Jane
5b11227f-2b5e-4da7-9a63-194534d32279
Edwards, Mark
818201d5-7636-4292-9af8-7dd8bcd1fcb5
Harrison, Seamus
ba3377b5-c7ea-40df-81ee-e00bb6fda889
Richards, Toby
fffe064a-a2c6-4d35-8ea9-128eda18f7fa
Ackland, Gareth
bb1ef7dd-0a25-4c8c-9963-9b216115468d

Cross, Jane, Edwards, Mark, Harrison, Seamus, Richards, Toby and Ackland, Gareth (2011) Morbidity following complex EVAR. International Journal of Surgery, 9 (7), 576-576. (doi:10.1016/j.ijsu.2011.07.400).

Record type: Article

Abstract

Objectives: patterns of morbidity are poorly characterized for patients undergoing complex EVAR. Evidence for complex endografts is based on case series and morbidity is often poorly reported. Multi organ dysfunction is described but the pathological events triggering this are uncertain. We hypothesised that early postoperative cardiac morbidity occurs as part of multi-organ dysfunction rather than as an isolated ischaemic event.

Methods: a prospective analysis of 41 patients undergoing complex EVAR was undertaken. Primary endpoint was development of cardiac morbidity, on postoperative day 3.

Results: 8 patients underwent thoracoabdominal, 29 juxtarenal fenestrated and 4 iliac branched graft AAA repair. There were 5 deaths, 3 of which were in emergency cases. The most common postoperative morbidities on day 5 were renal (50% of inpatients), respiratory (44%), gastrointestinal (25%) and cardiac (19%). Occurrence of cardiac morbidity on day 3 was associated with increased total morbidity on days 3, 5, 8 and 15 (P=.04).

Conclusions: complex EVAR patients suffer non-cardiac morbidity in line with major non-vascular surgery. Early postoperative cardiac morbidity is associated with multi-organ dysfunction in this population indicating a more global pathology. This highlights the need for further study into the aetiology of cardiac injury in this group.

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e-pub ahead of print date: 3 October 2011
Published date: 2011

Identifiers

Local EPrints ID: 436977
URI: http://eprints.soton.ac.uk/id/eprint/436977
ISSN: 1743-9191
PURE UUID: cba82838-d0b7-49ba-8650-63daa2c6cc5f

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Date deposited: 14 Jan 2020 18:34
Last modified: 16 Mar 2024 05:59

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Contributors

Author: Jane Cross
Author: Mark Edwards
Author: Seamus Harrison
Author: Toby Richards
Author: Gareth Ackland

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