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Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda

Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda
Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda
In sub-Saharan Africa, cryptococcosis is a frequent opportunistic infection and a major cause of death in patients with AIDS. 1,2 The disease is mainly recognized at the neuromeningitis stage and is diagnosed by microscopy and culture of cerebrospinal fluid (CSF). The identification of cryptococcal antigen (CRAG) by latex particle agglutination is highly sensitive, 3,4 and this technique is used routinely in Western countries. We evaluated the prevalence of CRAG in serum samples from adults with clinically advanced HIV infection and the proportion of CRAG-positive patients with neuromeningitis.
1525-4135
411-412
Tassie, J.
07014d34-d5be-419f-9f10-df89edc0af34
Pepper, L.
020e0f7a-9549-40db-ace2-5c688be3fb88
Fogg, Carole
42057537-d443-462a-8944-c804252c973b
Biraro, S.
7fd5a937-8fd2-44fc-b5b9-5360786951b1
Mayanja, B.
375aca60-d816-4f49-8204-7700374b3f0b
Andia, I.
27de8a0e-468d-4fd7-b745-6aafffa4916b
Paugam, A.
6d788aad-b82a-4e5c-9f3a-c6b6dc537ff8
Priotto, G.
d1b595d6-6d71-42ff-bc3d-4dbe35947cb7
Legros, D.
5d194279-9820-41ee-80b0-1b0385ca9678
Tassie, J.
07014d34-d5be-419f-9f10-df89edc0af34
Pepper, L.
020e0f7a-9549-40db-ace2-5c688be3fb88
Fogg, Carole
42057537-d443-462a-8944-c804252c973b
Biraro, S.
7fd5a937-8fd2-44fc-b5b9-5360786951b1
Mayanja, B.
375aca60-d816-4f49-8204-7700374b3f0b
Andia, I.
27de8a0e-468d-4fd7-b745-6aafffa4916b
Paugam, A.
6d788aad-b82a-4e5c-9f3a-c6b6dc537ff8
Priotto, G.
d1b595d6-6d71-42ff-bc3d-4dbe35947cb7
Legros, D.
5d194279-9820-41ee-80b0-1b0385ca9678

Tassie, J., Pepper, L., Fogg, Carole, Biraro, S., Mayanja, B., Andia, I., Paugam, A., Priotto, G. and Legros, D. (2003) Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda. JAIDS Journal of Acquired Immune Deficiency Syndromes, 33 (3), 411-412. (doi:10.1097/00126334-200307010-00019).

Record type: Article

Abstract

In sub-Saharan Africa, cryptococcosis is a frequent opportunistic infection and a major cause of death in patients with AIDS. 1,2 The disease is mainly recognized at the neuromeningitis stage and is diagnosed by microscopy and culture of cerebrospinal fluid (CSF). The identification of cryptococcal antigen (CRAG) by latex particle agglutination is highly sensitive, 3,4 and this technique is used routinely in Western countries. We evaluated the prevalence of CRAG in serum samples from adults with clinically advanced HIV infection and the proportion of CRAG-positive patients with neuromeningitis.

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Published date: 1 July 2003

Identifiers

Local EPrints ID: 436985
URI: http://eprints.soton.ac.uk/id/eprint/436985
ISSN: 1525-4135
PURE UUID: 7c63682b-d4a0-4480-babd-28812a3165c5
ORCID for Carole Fogg: ORCID iD orcid.org/0000-0002-3000-6185

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Date deposited: 14 Jan 2020 18:34
Last modified: 17 Mar 2024 03:56

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Contributors

Author: J. Tassie
Author: L. Pepper
Author: Carole Fogg ORCID iD
Author: S. Biraro
Author: B. Mayanja
Author: I. Andia
Author: A. Paugam
Author: G. Priotto
Author: D. Legros

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