Faecal microbiota transplantation for Clostridium difficile infection in the United Kingdom
Faecal microbiota transplantation for Clostridium difficile infection in the United Kingdom
Faecal microbiota transplantation (FMT) has been shown to be highly effective in treating recurrent Clostridium difficile infection, but to date there have been no data from the United Kingdom. An electronic survey was developed at Portsmouth Hospitals' National Health Service (NHS) Trust and sent out to UK hospital specialists utilizing the contact databases of the British Infection Association and the Royal College of Gastroenterologists. A total of 162 responses were received, representing nearly one in every seven of the United Kingdom's infection specialists and a response from one in every two UK NHS acute trusts or boards. Ninety-six per cent believe that the evidence base supports the use of FMT, and 94% reported consulting on at least one patient a year in whom they would recommend FMT. However, only 22% reported FMT use in their institution in the last 10 years, and 6% reported performing more than ten FMTs in the last 10 years. Concerns with patient acceptance, donor selection, availability of screened faecal solution, feasibility of procedure and availability of local expertise were reported as inhibiting the use of FMT. More than 90% of respondents would like access to regional guidelines, prescreened faecal solution and expert advice to facilitate implementation, and more than two thirds of respondents would support a regional FMT referral centre. A large gap exists in the United Kingdom between physicians desire to use FMT and the ability and facilities to provide it as a therapy at the bedside.
578-582
Porter, R.J.
ed84e9ce-ddaa-48e2-8c88-968962e9b357
Fogg, C.
42057537-d443-462a-8944-c804252c973b
1 June 2015
Porter, R.J.
ed84e9ce-ddaa-48e2-8c88-968962e9b357
Fogg, C.
42057537-d443-462a-8944-c804252c973b
Porter, R.J. and Fogg, C.
(2015)
Faecal microbiota transplantation for Clostridium difficile infection in the United Kingdom.
Clinical Microbiology and Infection, 21 (6), .
(doi:10.1016/j.cmi.2015.01.020).
Abstract
Faecal microbiota transplantation (FMT) has been shown to be highly effective in treating recurrent Clostridium difficile infection, but to date there have been no data from the United Kingdom. An electronic survey was developed at Portsmouth Hospitals' National Health Service (NHS) Trust and sent out to UK hospital specialists utilizing the contact databases of the British Infection Association and the Royal College of Gastroenterologists. A total of 162 responses were received, representing nearly one in every seven of the United Kingdom's infection specialists and a response from one in every two UK NHS acute trusts or boards. Ninety-six per cent believe that the evidence base supports the use of FMT, and 94% reported consulting on at least one patient a year in whom they would recommend FMT. However, only 22% reported FMT use in their institution in the last 10 years, and 6% reported performing more than ten FMTs in the last 10 years. Concerns with patient acceptance, donor selection, availability of screened faecal solution, feasibility of procedure and availability of local expertise were reported as inhibiting the use of FMT. More than 90% of respondents would like access to regional guidelines, prescreened faecal solution and expert advice to facilitate implementation, and more than two thirds of respondents would support a regional FMT referral centre. A large gap exists in the United Kingdom between physicians desire to use FMT and the ability and facilities to provide it as a therapy at the bedside.
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Accepted/In Press date: 22 January 2015
e-pub ahead of print date: 9 February 2015
Published date: 1 June 2015
Additional Information:
This is the peer reviewed version of the following article: R.J. Porter, C. Fogg, Faecal microbiota transplantation for Clostridium difficile infection in the United Kingdom, Clinical Microbiology and Infection, Volume 21, Issue 6, June 2015, Pages 578-582, ISSN 1198-743X, http://dx.doi.org/10.1016/j.cmi.2015.01.020., which has been published in final form at http://www.sciencedirect.com/science/article/pii/S1198743X15002463. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
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Local EPrints ID: 437066
URI: http://eprints.soton.ac.uk/id/eprint/437066
ISSN: 1198-743X
PURE UUID: ce397300-1645-4d21-ba1c-1b57e03e3b51
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Last modified: 17 Mar 2024 03:56
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