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Epigenetics in age related macular degeneration: new discoveries and future perspectives

Epigenetics in age related macular degeneration: new discoveries and future perspectives
Epigenetics in age related macular degeneration: new discoveries and future perspectives
The study of Epigenetics has explained some of the ‘missing heritability’ of Age
Related Macular Degeneration (AMD). The epigenome also provides a substantial
contribution to the organisation of the functional retina. There is emerging evidence of
specific epigenetic mechanisms associated with AMD. This ‘AMD epigenome’, may
offer the chance to develop novel AMD treatments.
Age-related macular degeneration, Retina epigenetics
1420-682X
1-12
Gemenetzi, M.
7a1e4e8b-4ca4-47d9-8485-32d382141284
Lotery, A.J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Gemenetzi, M.
7a1e4e8b-4ca4-47d9-8485-32d382141284
Lotery, A.J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514

Gemenetzi, M. and Lotery, A.J. (2020) Epigenetics in age related macular degeneration: new discoveries and future perspectives. Cellular and Molecular Life Sciences, 77 (5), 1-12. (doi:10.1007/s00018-019-03421-w).

Record type: Article

Abstract

The study of Epigenetics has explained some of the ‘missing heritability’ of Age
Related Macular Degeneration (AMD). The epigenome also provides a substantial
contribution to the organisation of the functional retina. There is emerging evidence of
specific epigenetic mechanisms associated with AMD. This ‘AMD epigenome’, may
offer the chance to develop novel AMD treatments.

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Epigenetics in Age Related Macular degeneration
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More information

Accepted/In Press date: 10 December 2019
e-pub ahead of print date: 2 January 2020
Keywords: Age-related macular degeneration, Retina epigenetics

Identifiers

Local EPrints ID: 437151
URI: http://eprints.soton.ac.uk/id/eprint/437151
ISSN: 1420-682X
PURE UUID: f9623e79-02f1-4822-a519-dfa6eb8ccaa8
ORCID for A.J. Lotery: ORCID iD orcid.org/0000-0001-5541-4305

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Date deposited: 20 Jan 2020 17:30
Last modified: 26 Nov 2021 02:47

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Contributors

Author: M. Gemenetzi
Author: A.J. Lotery ORCID iD

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