Infant milk feeding and bone health in later life: findings from the Hertfordshire Cohort Study
Infant milk feeding and bone health in later life: findings from the Hertfordshire Cohort Study
Summary: Using data from the Hertfordshire cohort study, this study examined the effect of breastfeeding and bottle feeding on adult lumbar spine and femoral neck bone mineral content (BMC) and bone mineral density (BMD). The type of infant milk feeding was significantly associated with lumbar spine BMD in males. Introduction: Using data from the Hertfordshire cohort study (HCS), this study aims to examine the effect of infant milk feeding on bone health in later life by comparing the effect of breastfeeding and bottle feeding on lumbar spine and femoral neck BMC and BMD. Methods: Information about infant milk feeding, birth weight (kg) and weight at 1 (kg) was collected by health visitors between 1931 and 1939 in Hertfordshire. BMC and BMD measurements were taken by DXA scan between 1998 and 2004. Linear regression models adjusted for conditional weight at 1, age at DXA scan, sex, adult BMI, smoking behaviour, alcohol consumption, physical activity, dietary calcium, and prudent diet score. Results: Infant milk feeding was significantly associated with lumbar spine BMD (b = − 0.028; 95% CI, − 0.055; − 0.000; p value, 0.047) in males. On average, males who consumed breastmilk alternatives in infancy had lower lumbar spine BMD measurements than those who were fed only breastmilk. These associations remained significant in fully adjusted models. There were no significant associations between infant milk feeding and bone health for females. Conclusions: Significant associations between infant milk feeding and lumbar spine BMD in males indicate that breastmilk may be protective for the bone health of male babies. The evidence presented here underscores the potential lifelong benefits of breastfeeding and may highlight the differences between osteoporotic risk factors for males and females.
Bone and bones, Bottle feeding, Breastfeeding, Osteoporosis
709-714
Carter, Sarah
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Parsons, Camille
9730e5c3-0382-4ed7-8eaa-6932ab09ec15
Robinson, Sian
ba591c98-4380-456a-be8a-c452f992b69b
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Ward, Kathryn
39bd4db1-c948-4e32-930e-7bec8deb54c7
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
1 April 2020
Carter, Sarah
a5111bba-b67c-47ec-b74a-b0bcef477fe6
Parsons, Camille
9730e5c3-0382-4ed7-8eaa-6932ab09ec15
Robinson, Sian
ba591c98-4380-456a-be8a-c452f992b69b
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Ward, Kathryn
39bd4db1-c948-4e32-930e-7bec8deb54c7
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Carter, Sarah, Parsons, Camille, Robinson, Sian, Harvey, Nicholas, Ward, Kathryn, Cooper, Cyrus and Dennison, Elaine
(2020)
Infant milk feeding and bone health in later life: findings from the Hertfordshire Cohort Study.
Osteoporosis International, 31 (4), .
(doi:10.1007/s00198-020-05296-1).
Abstract
Summary: Using data from the Hertfordshire cohort study, this study examined the effect of breastfeeding and bottle feeding on adult lumbar spine and femoral neck bone mineral content (BMC) and bone mineral density (BMD). The type of infant milk feeding was significantly associated with lumbar spine BMD in males. Introduction: Using data from the Hertfordshire cohort study (HCS), this study aims to examine the effect of infant milk feeding on bone health in later life by comparing the effect of breastfeeding and bottle feeding on lumbar spine and femoral neck BMC and BMD. Methods: Information about infant milk feeding, birth weight (kg) and weight at 1 (kg) was collected by health visitors between 1931 and 1939 in Hertfordshire. BMC and BMD measurements were taken by DXA scan between 1998 and 2004. Linear regression models adjusted for conditional weight at 1, age at DXA scan, sex, adult BMI, smoking behaviour, alcohol consumption, physical activity, dietary calcium, and prudent diet score. Results: Infant milk feeding was significantly associated with lumbar spine BMD (b = − 0.028; 95% CI, − 0.055; − 0.000; p value, 0.047) in males. On average, males who consumed breastmilk alternatives in infancy had lower lumbar spine BMD measurements than those who were fed only breastmilk. These associations remained significant in fully adjusted models. There were no significant associations between infant milk feeding and bone health for females. Conclusions: Significant associations between infant milk feeding and lumbar spine BMD in males indicate that breastmilk may be protective for the bone health of male babies. The evidence presented here underscores the potential lifelong benefits of breastfeeding and may highlight the differences between osteoporotic risk factors for males and females.
Text
070120 R.3 OI-Infant feeding and bone health in later life
- Accepted Manuscript
More information
Accepted/In Press date: 9 January 2020
e-pub ahead of print date: 15 February 2020
Published date: 1 April 2020
Additional Information:
Publisher Copyright:
© 2020, International Osteoporosis Foundation and National Osteoporosis Foundation.
Keywords:
Bone and bones, Bottle feeding, Breastfeeding, Osteoporosis
Identifiers
Local EPrints ID: 437155
URI: http://eprints.soton.ac.uk/id/eprint/437155
ISSN: 0937-941X
PURE UUID: 2d00c7d7-452a-4e14-a87e-50f759080cc5
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Date deposited: 20 Jan 2020 17:31
Last modified: 18 Mar 2024 05:07
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Contributors
Author:
Sarah Carter
Author:
Camille Parsons
Author:
Sian Robinson
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